Jump to content

Drilldown: Medicines

Pharmacopedia
BrowseCategoriesLog in

Choose a table:


Medicines > generic: Valsartan & fda max: 320 mg/d (hypertension); 320 mg/d (HF) & duration: 24 hours

Use the filters below to narrow your results.

generic: (Click arrow to add another value)
brand:
Diovan; Entresto (in fixed-dose combination with sacubitril) (1)
classes:
[[:Category:Angiotensin_receptor_blockers|Angiotensin receptor blocker (ARB)]] (1) · [[:Category:Antihypertensives|Antihypertensive]] (1)
mechanism:
'"`UNIQ--vote-000004C8-QINU`"' Largely hepatically cleared (~80% biliary); no active metabolite. Sacubitril-valsartan (Entresto) combines an ARB with neprilysin inhibition for HFrEF and was a notable advance over the ARB-alone trial (PARADIGM-HF, 2014)'"`UNIQ--ref-000004C9-QINU`"'. (1)
uses:
'"`UNIQ--vote-000004CA-QINU`"', '"`UNIQ--vote-000004CB-QINU`"', '"`UNIQ--vote-000004CC-QINU`"' (1)
starting dose:
80-160 mg PO once daily (40 mg BID in HFrEF, titrating up to 160 mg BID) (1)
preparations:
40, 80, 160, 320 mg tablets; oral suspension (1)
fda max: (Click arrow to add another value)
routes:
Oral (1)
onset:
BP effect 2 hours; max at 4-6 weeks (1)
duration: (Click arrow to add another value)
halflife:
~6 hours'"`UNIQ--ref-000004CD-QINU`"' (1)
bioavailability:
~25% (oral; food reduces absorption ~40%)'"`UNIQ--ref-000004CE-QINU`"' (1)
pregnancy:
'''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, hypocalvaria, hypotension. Stop on detection'"`UNIQ--ref-000004CF-QINU`"' (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

Showing below up to 1 result in range #1 to #1.

View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)


View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)

Retrieved from "https://pharmacopedia.wiki/p/Special:Drilldown/Medicines"