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Medicines > generic: Furosemide & fda max: 600 mg/d typical practical ceiling in heart failure & duration: IV: ~2 hours; PO: 6-8 hours

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generic: (Click arrow to add another value)
brand:
Lasix (1)
classes:
[[:Category:Diuretics|Diuretic]] (1) · [[:Category:Loop_diuretics|Loop diuretic]] (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-0000021C-QINU`"', '"`UNIQ--vote-0000021D-QINU`"', '"`UNIQ--vote-0000021E-QINU`"', '"`UNIQ--vote-0000021F-QINU`"', '"`UNIQ--vote-00000220-QINU`"', '"`UNIQ--vote-00000221-QINU`"' (1)
starting dose:
20-40 mg PO/IV; titrate by clinical response. In diuretic-resistant heart failure or CKD, doses to 200 mg or higher may be needed (1)
preparations:
20, 40, 80 mg tablets; 10 mg/mL oral solution; 10 mg/mL IV (1)
fda max: (Click arrow to add another value)
routes:
IM (1) · IV (1) · Oral (1)
onset:
IV: 5 minutes; PO: 30-60 minutes (1)
duration: (Click arrow to add another value)
halflife:
1.5-2 hours (longer in renal failure)'"`UNIQ--ref-00000222-QINU`"' (1)
bioavailability:
~50% (oral; highly variable, 10-100%, hence the standard 1:2 IV-to-PO conversion)'"`UNIQ--ref-00000223-QINU`"' (1)
pregnancy:
Avoid where possible; can reduce uteroplacental perfusion and produce neonatal electrolyte disturbance. Reserved for compelling indications.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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