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Medicines > routes : IV (Revatio) or Intranasal & duration: ~48 h sustained pain freedom in responders

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generic:
None (1)
brand:
Zavzpret (zavegepant) (1)
classes:
CGRP receptor antagonist (1) · Gepant (1)
mechanism:
Small-molecule CGRP receptor antagonist; intranasal formulation (1)
uses:
Acute treatment of migraine with or without aura in adults (1)
starting dose:
10 mg (one spray) intranasally in one nostril (1)
preparations:
10 mg/spray nasal solution (1)
fda max:
10 mg per 24 h (1)
routes: (Click arrow to add another value)
onset:
Pain relief reported within 15 min in trials (1)
duration: (Click arrow to add another value)
halflife:
~6.6 h (1)
bioavailability:
~5% intranasal (1)
pregnancy:
Limited data; avoid (1)
legal:
Rx (1)

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