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Medicines > fda max : 10 mg/d or 2550 mg/d (IR); 2000 mg/d (ER) & onset: LDL lowering within 2 weeks

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generic:
Ezetimibe (1)
brand:
Zetia (1)
classes:
[[:Category:Cholesterol_absorption_inhibitors|Cholesterol absorption inhibitor]] (1) · [[:Category:Lipid-lowering_agents|Lipid-lowering agent]] (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-0000044C-QINU`"', '"`UNIQ--vote-0000044D-QINU`"', '"`UNIQ--vote-0000044E-QINU`"', '"`UNIQ--vote-0000044F-QINU`"' (1)
starting dose:
10 mg PO once daily, with or without food (1)
preparations:
10 mg tablet; also as fixed-dose combinations with simvastatin (Vytorin) and atorvastatin (Liptruzet, withdrawn US 2015 but generics exist) (1)
fda max: (Click arrow to add another value)
routes:
Oral (1)
onset: (Click arrow to add another value)
duration:
24 hours (1)
halflife:
~22 hours (parent + active glucuronide)'"`UNIQ--ref-00000450-QINU`"' (1)
bioavailability:
Variable (oral; rapidly conjugated to active glucuronide; food does not affect)'"`UNIQ--ref-00000451-QINU`"' (1)
pregnancy:
Limited data; generally avoided particularly in combination with statin.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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