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Medicines > generic: Montelukast & fda max : 10 mg/d (adults) or 90 mg BID (acute year); 60 mg BID (chronic post-MI)

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generic: (Click arrow to add another value)
brand:
Singulair (1)
classes:
[[:Category:Antiasthmatic_agents|Antiasthmatic]] (1) · [[:Category:Leukotriene_receptor_antagonists|Leukotriene receptor antagonist]] (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-0000015B-QINU`"', '"`UNIQ--vote-0000015C-QINU`"', '"`UNIQ--vote-0000015D-QINU`"' (1)
starting dose:
10 mg PO once daily in the evening (adults); 4-5 mg in children (1)
preparations:
10 mg tablets; 4 mg, 5 mg chewables; 4 mg granules (1)
fda max: (Click arrow to add another value)
routes:
Oral (1)
onset:
Bronchodilation within 1-2 hours; full controller effect 1-2 weeks (1)
duration:
24 hours (1)
halflife:
2.7-5.5 hours'"`UNIQ--ref-0000015E-QINU`"' (1)
bioavailability:
~64% (oral; not significantly affected by food)'"`UNIQ--ref-0000015F-QINU`"' (1)
pregnancy:
Generally considered safe; pregnancy registries do not show increased major malformation risk.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US. '''FDA Boxed Warning (2020):''' neuropsychiatric events including agitation, depression, sleep disturbance, and suicidal thoughts; benefit-risk should be reassessed regularly'"`UNIQ--ref-00000160-QINU`"'. (1)

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