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Drilldown: Medicines

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Medicines > fda max : 100 mg/d or 40 mg/d & halflife: ~11 hours (enalaprilat, the active metabolite)'"`UNIQ--ref-00000B84-QINU`"'

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generic:
Enalapril (and enalaprilat IV) (1)
brand:
Vasotec, Vasotec IV, Epaned (1)
classes:
[[:Category:ACE_inhibitors|ACE inhibitor]] (1) · [[:Category:Antihypertensives|Antihypertensive]] (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-00000B81-QINU`"', '"`UNIQ--vote-00000B82-QINU`"', '"`UNIQ--vote-00000B83-QINU`"' (1)
starting dose:
5-10 mg PO once daily (2.5 mg if on diuretic or in heart failure); titrate to 10-20 mg BID for HFrEF (1)
preparations:
2.5, 5, 10, 20 mg tablets; 1 mg/mL oral solution (Epaned); 1.25 mg/mL IV (enalaprilat) (1)
fda max: (Click arrow to add another value)
routes:
IV (1) · Oral (1)
onset:
BP effect 1 hour; max at 4-6 hours (1)
duration:
12-24 hours (1)
halflife: (Click arrow to add another value)
bioavailability:
~60% (oral; food does not affect absorption)'"`UNIQ--ref-00000B85-QINU`"' (1)
pregnancy:
'''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, skull hypoplasia, hypotension. Stop on detection'"`UNIQ--ref-00000B86-QINU`"' (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)
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