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Medicines (732)

Medicines > generic: None

& fda max

: 195 units/treatment for chronic migraine; max varies by problem

or 40 mg/d

Use the filters below to narrow your results.

Botox (1) · Viibryd (1)

neuromuscular blocker (presynaptic) (1) · Neurotoxin (1) · Serotonin partial agonist reuptake inhibitor (SPARI) (1)

None (1) · Cleaves SNAP-25 protein in presynaptic motor and autonomic nerve terminals, blocking acetylcholine release; in chronic migraine, hypothesized to inhibit peripheral sensitization of trigeminovascular nociceptors (1)

Chronic migraine (≥15 headache days/month), cervical dystonia, blepharospasm, hyperhidrosis, overactive bladder, urinary incontinence, strabismus, spasticity, cosmetic problems (1) · Major depressive disorder in adults (FDA-approved 2011) (1)

10 mg PO once daily × 7 days, then 20 mg × 7 days, then 40 mg as target dose (take with food) (1) · Chronic migraine (PREEMPT protocol): 155 units divided across 31 sites in 7 head/neck muscle groups every 12 weeks (1)

10 mg, 20 mg, 40 mg tablets (1) · 50, 100, or 200 unit vials of lyophilized powder for reconstitution (1)

Intramuscular (PREEMPT injections for migraine) (1) · Oral (1)

1–2 weeks for muscle effects; preventive migraine benefit accrues over 12-week cycles (1) · 4-6 weeks for full antidepressant effect (claimed earlier onset for some patients due to 5HT1A partial agonism) (1)

Daily dosing (1) · ~12 weeks (1)

Tissue half-life not formally measured; clinical effect ~12 weeks (1) · ~25 hours (1)

Local (intramuscular) (1) · ~72% (with food); much lower fasting (~36%) (1)

Category C; limited data (1) · Limited data; weigh benefits/risks (1)

Rx (1) · Rx; black-box warning for distant spread of toxin effect (1)

Showing below up to 2 results in range #1 to #2.

O

Onabotulinumtoxin A

V

Vilazodone

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