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Medicines > generic: Telmisartan & fda max : 50 mg/day (no efficacy benefit shown for higher doses despite the 100 mg strength being available) or 80 mg/d

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generic: (Click arrow to add another value)
brand:
Micardis (1)
classes:
[[:Category:Angiotensin_receptor_blockers|Angiotensin receptor blocker (ARB)]] (1) · [[:Category:Antihypertensives|Antihypertensive]] (1)
mechanism:
'"`UNIQ--vote-00000AEA-QINU`"' The 24-hour half-life supports once-daily dosing with consistent overnight BP control. Largely hepatically cleared (~98% biliary); no significant renal clearance dependence'"`UNIQ--ref-00000AEB-QINU`"'. (1)
uses:
'"`UNIQ--vote-00000AEC-QINU`"', '"`UNIQ--vote-00000AED-QINU`"' (1)
starting dose:
40 mg PO once daily; titrate to 80 mg (1)
preparations:
20, 40, 80 mg tablets (1)
fda max: (Click arrow to add another value)
routes:
Oral (1)
onset:
BP effect within 1-2 weeks (1)
duration:
24 hours (1)
halflife:
~24 hours (longest of the ARB class; suits patients with morning BP surge)'"`UNIQ--ref-00000AEE-QINU`"' (1)
bioavailability:
42-58% (oral; dose-dependent)'"`UNIQ--ref-00000AEF-QINU`"' (1)
pregnancy:
'''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, hypocalvaria, hypotension. Stop on detection'"`UNIQ--ref-00000AF0-QINU`"' (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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