Jump to content

Drilldown: Medicines

Pharmacopedia
BrowseCategoriesLog in
Pharmacopedia is being built in public. Pages may be incomplete.About this site

Choose a table:


Medicines > generic : Protriptyline or None & fda max: 2 tablets/day (dextromethorphan 90 mg / bupropion 210 mg)

Use the filters below to narrow your results.

generic: (Click arrow to add another value)
brand:
Auvelity (dextromethorphan/bupropion ER) (1)
classes:
NMDA receptor antagonist + sigma-1 agonist + NDRI (combination) (1)
mechanism:
None (1)
uses:
Major depressive disorder in adults (FDA-approved August 2022) (1)
starting dose:
1 tablet (dextromethorphan 45 mg / bupropion 105 mg) PO daily × 3 days, then increase to 1 tablet BID (1)
preparations:
Dextromethorphan 45 mg + bupropion 105 mg ER tablets (1)
fda max: (Click arrow to add another value)
routes:
Oral (1)
onset:
Significant antidepressant response by week 1 in trials (faster than monoaminergic antidepressants which take 4-6 weeks) (1)
duration:
Sustained with twice-daily dosing (1)
halflife:
Dextromethorphan ~22 h (when CYP2D6 inhibited); bupropion ~21 h (1)
bioavailability:
Not formally characterized for the combination (1)
pregnancy:
Limited data; avoid (1)
legal:
Rx (1)

Showing below up to 1 result in range #1 to #1.

View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)


View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)

Retrieved from "https://pharmacopedia.wiki/p/Special:Drilldown/Medicines"