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Medicines > generic: Ramipril & fda max: 20 mg/d (hypertension); 10 mg/d (other indications typical)

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generic: (Click arrow to add another value)
brand:
Altace (1)
classes:
[[:Category:ACE_inhibitors|ACE inhibitor]] (1) · [[:Category:Antihypertensives|Antihypertensive]] (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-00000C2E-QINU`"', '"`UNIQ--vote-00000C2F-QINU`"', '"`UNIQ--vote-00000C30-QINU`"', '"`UNIQ--vote-00000C31-QINU`"' (1)
starting dose:
2.5 mg PO once daily (1.25 mg in CHF or volume depletion); titrate to 5-10 mg/d (1)
preparations:
1.25, 2.5, 5, 10 mg capsules (1)
fda max: (Click arrow to add another value)
routes:
Oral (1)
onset:
BP effect 1-2 hours; max at 6 hours (1)
duration:
24 hours (1)
halflife:
~13-17 hours (ramiprilat, the active metabolite)'"`UNIQ--ref-00000C32-QINU`"' (1)
bioavailability:
~28% (oral; food slows but does not reduce absorption)'"`UNIQ--ref-00000C33-QINU`"' (1)
pregnancy:
'''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, skull hypoplasia, hypotension'"`UNIQ--ref-00000C34-QINU`"' (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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