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Medicines > generic: Celecoxib & fda max: 400 mg/day for chronic indications; higher for short-term acute pain

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generic: (Click arrow to add another value)
brand:
Celebrex (oral capsules), Elyxyb (oral solution, for acute migraine) (1)
classes:
selective COX-2)]] (1) · [[:Category:Analgesics|Analgesic]] (1) · [[:Category:NSAIDs|Non-steroidal anti-inflammatory (NSAID (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"', '"`UNIQ--vote-00000023-QINU`"', '"`UNIQ--vote-00000024-QINU`"', '"`UNIQ--vote-00000025-QINU`"', '"`UNIQ--vote-00000026-QINU`"', '"`UNIQ--vote-00000027-QINU`"', '"`UNIQ--vote-00000028-QINU`"' (1)
starting dose:
Osteoarthritis: 200 mg PO once daily or 100 mg BID. Rheumatoid arthritis: 100-200 mg PO BID. Acute pain: 400 mg loading, then 200 mg every 12 hours (1)
preparations:
Capsules 50, 100, 200, 400 mg; Elyxyb oral solution 25 mg/mL (1)
fda max: (Click arrow to add another value)
routes:
Oral (1)
onset:
30-60 minutes (1)
duration:
12-24 hours (1)
halflife:
~11 hours'"`UNIQ--ref-00000029-QINU`"' (1)
bioavailability:
~99% (oral)'"`UNIQ--ref-0000002A-QINU`"' (1)
pregnancy:
Avoid from 20 weeks gestation onward per FDA's 2020 expanded NSAID warning (fetal renal dysfunction, oligohydramnios); contraindicated from 30 weeks (risk of premature ductus arteriosus closure)'"`UNIQ--ref-0000002B-QINU`"' (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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