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Choose a table:
Medicines (732)
Medicines
> generic:
Linagliptin
&
uses:
'"`UNIQ--vote-0000117B-QINU`"'
&
fda max:
5 mg/d
Use the filters below to narrow your results.
generic:
(Click arrow to add another value)
None
·
Codeine
·
1,4-Butanediol
·
1B-LSD
·
1cP-LSD
·
1P-LSD
·
1V-LSD
·
2-AI
·
2-FA
·
2-FDCK
·
2-FMA
·
25B-NBOH
·
25B-NBOMe
·
25C-NBOH
·
25C-NBOMe
·
25I-NBOH
·
25I-NBOMe
·
25N-NBOMe
·
2C-B
·
2C-B-FLY
Other values:
2C-C
2C-D
2C-E
2C-I
2C-P
2C-T-2
2C-T-7
3,4-CTMP
3-FA
3-FMA
3-HO-PCE
3-HO-PCP
3-MMC
3-MeO-PCE
3-MeO-PCP
4-AcO-DET
4-AcO-DMT
4-AcO-DiPT
4-AcO-MET
4-AcO-MiPT
4-FA
4-FMA
4-HO-DET
4-HO-DPT
4-HO-DiPT
4-HO-EPT
4-HO-MET
4-HO-MiPT
4-MeO-PCP
4F-EPH
4F-MPH
5,6-MDO-DMT
5-APB
5-HTP
5-MAPB
5-MeO-DALT
5-MeO-DMT
5-MeO-DiPT
5-MeO-MiPT
5F-AKB48
5F-PB-22
6-APB
6-APDB
7-Hydroxymitragynine
AB-FUBINACA
AL-LAD
ALD-52
APICA
Acacia confusa
Acamprosate
Acetaminophen (paracetamol, APAP)
Acetylfentanyl
Acyclovir
Adalimumab
Adrafinil
Agomelatine
Albuterol
Alendronate
Alfentanil
Allopurinol
Allylescaline
Almotriptan
Alprazolam
Amanita muscaria
Amantadine
Amiodarone
Amitriptyline (hydrochloride)
Amlodipine
Amobarbital
Amoxapine
Amoxicillin
Anadenanthera colubrina
Anadenanthera peregrina
Anastrozole
Aniracetam
Apixaban
Apomorphine
Aripiprazole
Armodafinil
Artemisia absinthium
Ascorbic acid (vitamin C)
Asenapine
Aspirin (acetylsalicylic acid; ASA)
Atenolol
Atogepant
Atomoxetine
Atorvastatin
Atropa belladonna
Atropine
Avanafil
Ayahuasca
Azelastine
Azithromycin
Baclofen
Baeocystin
Banisteriopsis caapi
Benazepril
Benzocaine
Benzonatate
Benztropine
Benzydamine
Betamethasone (valerate, dipropionate, sodium phosphate, acetate)
Betel
Bimatoprost
Biperiden
Bisacodyl
Bisoprolol
Black Drink
Blue lotus
Brimonidine
Brivaracetam
Bromantane
Bromazepam
Bromazolam
Bromo-DragonFLY
Bromocriptine
Brompheniramine
Brugmansia
Budesonide
Bufo alvarius
Bufotenin
Bumetanide
Bupivacaine
Buprenorphine
Buprenorphine / Naloxone
Bupropion
Bupropion / Naltrexone
Buspirone
Butalbital
Butalbital / Acetaminophen / Caffeine
Butalbital / Aspirin / Caffeine
Butorphanol
Butylone
Cabergoline
Caffeine
Calcitriol (1,25-dihydroxyvitamin D3)
Calcium (carbonate, citrate, gluconate, chloride salts)
Calea zacatechichi
Cannabidiol
Cannabigerol
Cannabinol
Carbamazepine
Carbidopa/levodopa
Carfentanil
Carisoprodol
Carvedilol
Cathinone
Cefdinir
Cefuroxime (axetil oral, sodium IV)
Celecoxib
Cenobamate
Cephalexin
Cetirizine
Chlordiazepoxide
Chlorhexidine gluconate (CHG)
Chloroform
Chlorpheniramine
Chlorpromazine
Chlorthalidone
Chlorzoxazone
Chocolate
Cholecalciferol (vitamin D3)
Ciclopirox
Ciprofloxacin
Citalopram
Clindamycin
Clobazam
Clobetasol propionate
Clomipramine
Clonazepam
Clonazolam
Clonidine
Clopidogrel
Clorazepate
Clotrimazole
Clozapine
Coca
Cocaine
Codeine / Acetaminophen
Coffee
Colchicine
Coluracetam
Curare
Cyanocobalamin (vitamin B12)
Cyclazodone
Cyclobenzaprine
Cyclosporine (ciclosporin)
Cyproheptadine (hydrochloride)
DET
DMT
DOB
DOC
DOI
DOM
DPT
Dapagliflozin
Datura
Delta-10-THC
Delta-8-THC
Deschloroetizolam
Deschloroketamine
Desflurane
Desipramine
Desomorphine
Desoxypipradrol
Desvenlafaxine (succinate)
Dexamethasone
Dexmedetomidine
Dexmethylphenidate
Dextroamphetamine
Dextromethorphan
Dextromethorphan / Quinidine
Dextropropoxyphene
Dextrorphan
DiPT
Diacetylmorphine
Diazepam
Diclazepam
Diclofenac (sodium, potassium, epolamine; multiple salt forms)
Dicyclomine
Diethyl ether
Dihydrocodeine
Dihydroergotamine
Diltiazem
Dimenhydrinate
Diphenhydramine (hydrochloride; citrate)
Diphenidine
Disulfiram
Docusate (sodium or calcium)
Donepezil
Dorzolamide
Doxazosin
Doxepin (hydrochloride)
Doxycycline
Doxylamine
Dronabinol
Droperidol
Dulaglutide
Duloxetine
Dutasteride
EPT
ETH-LAD
Eletriptan
Empagliflozin
Enalapril (and enalaprilat IV)
Entacapone
Ephedrine
Ephenidine
Ephylone
Epinephrine (adrenaline)
Ergocalciferol (vitamin D2)
Ergotamine
Erythromycin
Escaline
Escitalopram
Eslicarbazepine
Esmolol
Esomeprazole
Estazolam
Estradiol (17β-estradiol)
Eszopiclone
Ethcathinone
Ethchlorvynol
Ethosuximide
Ethylmorphine
Ethylone
Ethylphenidate
Eticyclidine
Etizolam
Etodolac
Etomidate
Evolocumab
Exenatide
Ezetimibe
F-Phenibut
Famotidine
Felbamate
Fenethylline
Fenfluramine
Fenofibrate
Fentanyl
Ferrous sulfate
Fexofenadine
Finasteride
Flecainide
Flibanserin
Flualprazolam
Flubromazepam
Flubromazolam
Fluconazole
Flunitrazepam
Flunitrazolam
Fluorouracil (5-FU)
Fluoxetine
Fluphenazine
Flurazepam
Fluticasone
Fluvoxamine (maleate)
Folic acid (folate, pteroylglutamic acid)
Fosphenytoin
Frovatriptan
Furosemide
GBL
GHB
Gabapentin
Gaboxadol
Galantamine
Glimepiride
Glipizide
Glutethimide
Guaifenesin
Guanfacine
Guarana
HHC
Haloperidol
Halothane
Harmaline
Harmine
Hawaiian Baby Woodrose
Hexedrone
Hydralazine
Hydrochlorothiazide
Hydrocodone
Hydrocortisone (cortisol)
Hydromorphone
Hydroquinone
Hydroxychloroquine
Hydroxyzine (hydrochloride; pamoate salt)
Hyoscyamine
Hyoscyamus niger
Iboga
Ibogaine
Ibotenic acid
Ibuprofen
Icosapent ethyl (eicosapentaenoic acid ethyl ester, EPA-EE)
Iloperidone
Imipramine
Indomethacin
Insulin aspart
Insulin degludec
Insulin detemir
Insulin glargine
Insulin lispro
Ipratropium bromide
Irbesartan
Isocarboxazid
Isoflurane
Isopropylphenidate
Isosorbide (dinitrate, mononitrate)
Ivermectin
JWH-018
JWH-073
Kava
Ketoconazole
Ketorolac (tromethamine)
Ketotifen
Khat
Kola
Kratom
L-Theanine
LSA
LSD
LSH
LSZ
Labetalol
Lacosamide
Lactated Ringer's solution
Lactulose
Lamotrigine
Lasmiditan
Latanoprost
Levetiracetam
Levocetirizine
Levodopa
Levofloxacin
Levomilnacipran
Levorphanol
Levothyroxine
Lidocaine (hydrochloride)
Linaclotide
Linagliptin
Liothyronine (T3, triiodothyronine sodium)
Liraglutide
Lisdexamfetamine (dimesylate)
Lisinopril
Lixisenatide
Lofexidine
Loperamide
Loratadine
Lorazepam
Lormetazepam
Losartan
Lovastatin
Loxapine
Lurasidone
MDA
MDAI
MDEA
MDMA
MDPV
MET
Magnesium (oxide, citrate, sulfate, hydroxide, gluconate, chloride salts)
Mandragora officinarum
Maprotiline
Meclizine
Medroxyprogesterone acetate (MPA)
Melatonin (N-acetyl-5-methoxytryptamine)
Meloxicam
Memantine
Memantine ER / Donepezil
Meperidine
Mephedrone
Meprobamate
Mesalamine (5-aminosalicylic acid, 5-ASA)
Mescal Bean
Metaxalone
Metformin
Methadone
Methallylescaline
Methamphetamine
Methaqualone
Methcathinone
Methimazole (thiamazole)
Methiopropamine
Methocarbamol
Methohexital
Methotrexate
Methoxetamine
Methylnaphthidate
Methylone
Methylphenidate
Methylprednisolone
Metizolam
Metoclopramide
Metoprolol
Metronidazole
Mexedrone
MiPLA
MiPT
Midazolam
Milnacipran
Mimosa hostilis
Mirabegron
Mirtazapine
Mitragynine
Mixed amphetamine salts
Moclobemide
Modafinil
Molindone
Mometasone furoate
Montelukast
Morning Glory
Morphine (sulfate)
Moxifloxacin
Mupirocin
Muscimol
Myristicin
N-Ethylhexedrone
N-Ethylpentedrone
NM-2-AI
Nabilone
Nabiximols
Nabumetone
Nadolol
Nalbuphine
Nalmefene
Naloxone
Naltrexone
Naproxen (sodium; free acid)
Naratriptan
Nebivolol
Nefazodone
Niacin (nicotinic acid, vitamin B3)
Nicotine
Nifedipine
Nifoxipam
Nitrazepam
Nitrofurantoin
Nitroglycerin (glyceryl trinitrate, GTN)
Nitromethaqualone
Nitrous oxide
Noopept
Norethindrone (norethisterone outside US)
Nortriptyline (hydrochloride)
Nutmeg
Nystatin
O-Desmethyltramadol
O-PCE
Ofloxacin
Olanzapine
Olanzapine / Fluoxetine
Olmesartan (medoxomil)
Olopatadine
Omega-3-acid ethyl esters
Omeprazole
Ondansetron
Opicapone
Orphenadrine
Oseltamivir
Oxazepam
Oxcarbazepine
Oxiracetam
Oxybutynin
Oxycodone (hydrochloride)
Oxycodone / Acetaminophen
Oxycodone / Aspirin
Oxymorphone
PMA
PMMA
PRO-LAD
Paliperidone
Pantoprazole
Papaverine
Paracetamol
Paroxetine (HCl; mesylate as Pexeva)
Penicillin G (benzylpenicillin; potassium, sodium, benzathine, procaine salts)
Penicillin V (phenoxymethylpenicillin)
Pentazocine
Pentedrone
Pentobarbital
Perampanel
Perphenazine
Peyote
Phalaris arundinaceae
Phenazopyridine
Phencyclidine
Phenelzine
Phenethylamine
Phenibut
Phenobarbital
Phentermine
Phenylpiracetam
Phenytoin
Pimozide
Pioglitazone
Piracetam
Piroxicam
Polyethylene glycol 3350 (PEG 3350)
Polyethylene glycol 3350 with electrolytes
Potassium chloride
Pramipexole
Pramiracetam
Pravastatin
Prazosin
Prednisolone (and prednisolone sodium phosphate, acetate, etc.)
Prednisone
Pregabalin
Primidone
Procaine
Prochlorperazine
Progesterone (micronized)
Prolintane
Promethazine (hydrochloride)
Propofol
Propranolol
Propylhexedrine
Proscaline
Protriptyline
Pseudoephedrine (hydrochloride; sulfate)
Psilocin
Psilocybin
Psilocybin mushrooms
Psychotria viridis
Pyrazolam
Quazepam
Quetiapine
RTI-111
Ramelteon
Ramipril
Rasagiline
Reboxetine
Remifentanil
Riboflavin (vitamin B2)
Rimegepant
Risperidone
Rivaroxaban
Rivastigmine
Rizatriptan (benzoate)
Ropinirole
Ropivacaine
Rosuvastatin
Rotigotine
Rufinamide
STS-135
Safinamide
Salvia divinorum
Salvinorin A
San Pedro cactus
Scopolamine
Secobarbital
Selegiline
Semaglutide
Semax
Sertraline
Sevoflurane
Sildenafil
Simvastatin
Sitagliptin
Sodium Oxybate
Sodium bicarbonate
Sodium chloride
Sodium fluoride
Solifenacin
Sotalol
Spironolactone
Stiripentol
Sucralfate
Sufentanil
Sumatriptan (succinate)
Sumatriptan / Naproxen
Syrian rue
THC
THCP
THJ-018
THJ-2201
TMA-2
Tadalafil
Tamsulosin
Tapentadol
Tasimelteon
Tea
Telmisartan
Temazepam
Terazosin
Terbinafine
Testosterone
Tetrahydrocannabivarin
Tetrahydroharmine
Theacrine
Thebaine
Theophylline
Thiopental
Thioridazine
Thiothixene
Thyroid (desiccated)
Tiagabine
Tianeptine
Ticagrelor
Timolol (maleate)
Tiotropium
Tirzepatide
Tizanidine
Tobramycin
Tolcapone
Topiramate
Torsemide
Tramadol
Tramadol / Acetaminophen
Tranylcypromine
Trazodone
Tretinoin (all-trans retinoic acid, ATRA)
Triamcinolone (acetonide and other esters)
Triazolam
Trifluoperazine
Trihexyphenidyl
Trimipramine
U-47700
Ubrogepant
Valacyclovir
Valproate (valproic acid, divalproex sodium, sodium valproate)
Valproic acid
Valsartan
Vardenafil
Varenicline
Venlafaxine
Verapamil
Vigabatrin
Vitamin E (α-tocopherol; mixed natural and synthetic forms)
Warfarin
Xenon
Yerba mate
Yopo
Zaleplon
Ziprasidone
Zolmitriptan
Zolpidem (tartrate)
Zonisamide
Zopiclone
aMT
alpha-PHP
alpha-PVP
ketamine
lithium
mCPP
mescaline
opium
Search
brand:
Tradjenta; with metformin Jentadueto (1)
classes:
[[:Category:Antihyperglycemic_agents|Antihyperglycemic agent]] (1)
·
[[:Category:DPP-4_inhibitors|DPP-4 inhibitor]] (1)
·
[[:Category:Incretin_modulators|Incretin pathway modulator]] (1)
mechanism:
None
(1)
uses:
(Click arrow to add another value)
None
·
'"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"', '"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"', '"`UNIQ--vote-00000023-QINU`"', '"`UNIQ--vote-00000024-QINU`"', '"`UNIQ--vote-00000025-QINU`"'
·
'"`UNIQ--vote-00000008-QINU`"', '"`UNIQ--vote-00000009-QINU`"'
·
'"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"'
·
'"`UNIQ--vote-00000017-QINU`"', '"`UNIQ--vote-00000018-QINU`"', '"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"'
·
'"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"', '"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"'
·
'"`UNIQ--vote-00000006-QINU`"'
·
'"`UNIQ--vote-00000017-QINU`"', '"`UNIQ--vote-00000018-QINU`"', '"`UNIQ--vote-00000019-QINU`"'
·
'"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"', '"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"'
·
'"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"', '"`UNIQ--vote-00000023-QINU`"', '"`UNIQ--vote-00000024-QINU`"', '"`UNIQ--vote-00000025-QINU`"', '"`UNIQ--vote-00000026-QINU`"', '"`UNIQ--vote-00000027-QINU`"', '"`UNIQ--vote-00000028-QINU`"'
·
'"`UNIQ--vote-00000013-QINU`"', '"`UNIQ--vote-00000014-QINU`"'
·
'"`UNIQ--vote-00000015-QINU`"', '"`UNIQ--vote-00000016-QINU`"'
·
Preventive treatment of migraine in adults (episodic and chronic)
·
'"`UNIQ--vote-00000015-QINU`"', '"`UNIQ--vote-00000016-QINU`"', '"`UNIQ--vote-00000017-QINU`"'
·
(investigational) '"`UNIQ--vote-000000EF-QINU`"', '"`UNIQ--vote-000000F0-QINU`"', '"`UNIQ--vote-000000F1-QINU`"', '"`UNIQ--vote-000000F2-QINU`"', '"`UNIQ--vote-000000F3-QINU`"'
·
Acute treatment of migraine with or without aura in adults
·
ADHD in children (6+), adolescents, and adults (FDA-approved 2021 for pediatric, 2022 for adult)
·
ADHD, narcolepsy
·
Alzheimer disease (FDA accelerated approval June 2021; '''withdrawn from market January 2024''' by manufacturer Biogen). At time of approval indicated for MCI or mild dementia stage of AD.
·
Alzheimer disease (MCI or mild dementia stage), FDA-approved July 2024
Other values:
Alzheimer disease (MCI or mild dementia stage); FDA accelerated approval Jan 2023 → traditional approval July 2023
Antimanic, Antidepressive, Antisuicide
Chronic migraine (≥15 headache days/month), cervical dystonia, blepharospasm, hyperhidrosis, overactive bladder, urinary incontinence, strabismus, spasticity, cosmetic problems
Depression, anxiety, neuropathic pain, fibromyalgia, chronic musculoskeletal pain
Excessive daytime sleepiness in adults with narcolepsy or obstructive sleep apnea (OSA)
Excessive daytime sleepiness or cataplexy in adults with narcolepsy (FDA-approved August 2019)
Hallucinations and delusions associated with Parkinson's disease psychosis (PDP). Investigational for psychosis in other dementias and as augmentation for depression.
Insomnia (sleep onset and/or maintenance) in adults (FDA-approved August 2014). Also studied for insomnia in mild-moderate Alzheimer disease.
Insomnia (sleep onset and/or maintenance) in adults (FDA-approved Dec 2019)
Insomnia (sleep onset and/or sleep maintenance) in adults (FDA-approved Jan 2022)
Investigational for major depressive disorder; trials underway (phase 3 mixed results)
Major depressive disorder in adults (FDA-approved 2011)
Major depressive disorder in adults (FDA-approved 2013). Notable for evidence of cognitive benefit (processing speed) that distinguishes it from other antidepressants.
Major depressive disorder in adults (FDA-approved August 2022)
Mild to moderate pain; cough suppression (low-dose).
No approved medical problem. Encountered as a designer/research benzodiazepine and, increasingly, as an adulterant in illicit opioid supplies.
Pain, cough, disquiet
Postpartum depression (PPD) in adults
Postpartum depression (PPD) in adults (FDA-approved 2023)
Preventive treatment of migraine in adults
Preventive treatment of migraine in adults; episodic cluster headache
Schizophrenia (FDA-approved 2015). Acute manic or mixed episodes of bipolar I disorder. Bipolar I depression (FDA-approved 2019). Adjunctive treatment of major depressive disorder (FDA-approved Dec 2022).
Schizophrenia (FDA-approved 2015). Adjunctive treatment of major depressive disorder (2015). '''Agitation associated with dementia due to Alzheimer disease''' (FDA-approved May 2023, first agent specifically approved for this problem). Investigational for PTSD (combined with sertraline).
Schizophrenia (FDA-approved Dec 2019). Bipolar depression as monotherapy or adjunct to lithium/valproate (FDA-approved Dec 2021).
Schizophrenia, acute psychosis, agitation, delirium, Tourette syndrome, severe nausea
Treatment-resistant depression (TRD) in adults, as adjunct to oral antidepressant (FDA-approved March 2019). Depressive symptoms in adults with MDD with acute suicidal ideation or behavior (FDA-approved Aug 2020).
[[Type 2 diabetes mellitus]] (adjunct, second-line)
[[Type 2 diabetes mellitus]] (incl. pediatric ≥10 y) · [[Obesity]] (incl. pediatric ≥12 y) · [[Cardiovascular risk reduction]] in T2DM
[[Type 2 diabetes mellitus]] · [[Cardiovascular risk reduction]] in T2DM
[[Type 2 diabetes mellitus]] · [[Obesity]] · [[Cardiovascular risk reduction]] in obesity without diabetes · [[MASH]] with stage 2–3 fibrosis · [[Chronic kidney disease]] in T2DM
[[Type 2 diabetes mellitus]] · [[Obesity]] · [[Obstructive sleep apnea]] in obesity
'"`UNIQ--vote-0000000C-QINU`"', '"`UNIQ--vote-0000000D-QINU`"', '"`UNIQ--vote-0000000E-QINU`"', '"`UNIQ--vote-0000000F-QINU`"'
'"`UNIQ--vote-00000011-QINU`"'
'"`UNIQ--vote-00000013-QINU`"'
'"`UNIQ--vote-00000017-QINU`"'
'"`UNIQ--vote-00000018-QINU`"', '"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"'
'"`UNIQ--vote-00000018-QINU`"', '"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"', '"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"'
'"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"', '"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"'
'"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"'
'"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"'
'"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"'
'"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"', '"`UNIQ--vote-00000021-QINU`"'
'"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"', '"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"', '"`UNIQ--vote-00000023-QINU`"', '"`UNIQ--vote-00000024-QINU`"', '"`UNIQ--vote-00000025-QINU`"', '"`UNIQ--vote-00000026-QINU`"'
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'"`UNIQ--vote-00000C0A-QINU`"', '"`UNIQ--vote-00000C0B-QINU`"', '"`UNIQ--vote-00000C0C-QINU`"', '"`UNIQ--vote-00000C0D-QINU`"', '"`UNIQ--vote-00000C0E-QINU`"'
'"`UNIQ--vote-00000C2E-QINU`"', '"`UNIQ--vote-00000C2F-QINU`"', '"`UNIQ--vote-00000C30-QINU`"', '"`UNIQ--vote-00000C31-QINU`"'
'"`UNIQ--vote-00000C4C-QINU`"', '"`UNIQ--vote-00000C4D-QINU`"'
'"`UNIQ--vote-00000C6D-QINU`"', '"`UNIQ--vote-00000C6E-QINU`"', '"`UNIQ--vote-00000C6F-QINU`"', '"`UNIQ--vote-00000C70-QINU`"', '"`UNIQ--vote-00000C71-QINU`"'
'"`UNIQ--vote-00000C8F-QINU`"', '"`UNIQ--vote-00000C90-QINU`"', '"`UNIQ--vote-00000C91-QINU`"'
'"`UNIQ--vote-00000CB0-QINU`"', '"`UNIQ--vote-00000CB1-QINU`"', '"`UNIQ--vote-00000CB2-QINU`"'
'"`UNIQ--vote-00000CCA-QINU`"', '"`UNIQ--vote-00000CCB-QINU`"'
'"`UNIQ--vote-00000CEF-QINU`"', '"`UNIQ--vote-00000CF0-QINU`"', '"`UNIQ--vote-00000CF1-QINU`"', '"`UNIQ--vote-00000CF2-QINU`"', '"`UNIQ--vote-00000CF3-QINU`"', '"`UNIQ--vote-00000CF4-QINU`"'
'"`UNIQ--vote-00000D13-QINU`"', '"`UNIQ--vote-00000D14-QINU`"', '"`UNIQ--vote-00000D15-QINU`"', '"`UNIQ--vote-00000D16-QINU`"'
'"`UNIQ--vote-00000D38-QINU`"', '"`UNIQ--vote-00000D39-QINU`"', '"`UNIQ--vote-00000D3A-QINU`"', '"`UNIQ--vote-00000D3B-QINU`"', '"`UNIQ--vote-00000D3C-QINU`"', '"`UNIQ--vote-00000D3D-QINU`"'
'"`UNIQ--vote-00000D57-QINU`"', '"`UNIQ--vote-00000D58-QINU`"'
'"`UNIQ--vote-00000D7C-QINU`"', '"`UNIQ--vote-00000D7D-QINU`"', '"`UNIQ--vote-00000D7E-QINU`"', '"`UNIQ--vote-00000D7F-QINU`"', '"`UNIQ--vote-00000D80-QINU`"', '"`UNIQ--vote-00000D81-QINU`"'
'"`UNIQ--vote-00000D9E-QINU`"', '"`UNIQ--vote-00000D9F-QINU`"', '"`UNIQ--vote-00000DA0-QINU`"'
'"`UNIQ--vote-00000DBE-QINU`"', '"`UNIQ--vote-00000DBF-QINU`"', '"`UNIQ--vote-00000DC0-QINU`"', '"`UNIQ--vote-00000DC1-QINU`"'
'"`UNIQ--vote-00000DDF-QINU`"', '"`UNIQ--vote-00000DE0-QINU`"', '"`UNIQ--vote-00000DE1-QINU`"', '"`UNIQ--vote-00000DE2-QINU`"'
'"`UNIQ--vote-00000DFC-QINU`"', '"`UNIQ--vote-00000DFD-QINU`"'
'"`UNIQ--vote-00000E23-QINU`"', '"`UNIQ--vote-00000E24-QINU`"', '"`UNIQ--vote-00000E25-QINU`"', '"`UNIQ--vote-00000E26-QINU`"', '"`UNIQ--vote-00000E27-QINU`"', '"`UNIQ--vote-00000E28-QINU`"', '"`UNIQ--vote-00000E29-QINU`"', '"`UNIQ--vote-00000E2A-QINU`"'
'"`UNIQ--vote-00000E4C-QINU`"', '"`UNIQ--vote-00000E4D-QINU`"', '"`UNIQ--vote-00000E4E-QINU`"', '"`UNIQ--vote-00000E4F-QINU`"', '"`UNIQ--vote-00000E50-QINU`"', '"`UNIQ--vote-00000E51-QINU`"'
'"`UNIQ--vote-00000E71-QINU`"', '"`UNIQ--vote-00000E72-QINU`"', '"`UNIQ--vote-00000E73-QINU`"', '"`UNIQ--vote-00000E74-QINU`"', '"`UNIQ--vote-00000E75-QINU`"'
'"`UNIQ--vote-00000E91-QINU`"', '"`UNIQ--vote-00000E92-QINU`"', '"`UNIQ--vote-00000E93-QINU`"'
'"`UNIQ--vote-00000EAF-QINU`"', '"`UNIQ--vote-00000EB0-QINU`"', '"`UNIQ--vote-00000EB1-QINU`"'
'"`UNIQ--vote-00000ECF-QINU`"', '"`UNIQ--vote-00000ED0-QINU`"', '"`UNIQ--vote-00000ED1-QINU`"', '"`UNIQ--vote-00000ED2-QINU`"'
'"`UNIQ--vote-00000EF4-QINU`"', '"`UNIQ--vote-00000EF5-QINU`"', '"`UNIQ--vote-00000EF6-QINU`"', '"`UNIQ--vote-00000EF7-QINU`"', '"`UNIQ--vote-00000EF8-QINU`"'
'"`UNIQ--vote-00000F1B-QINU`"', '"`UNIQ--vote-00000F1C-QINU`"', '"`UNIQ--vote-00000F1D-QINU`"', '"`UNIQ--vote-00000F1E-QINU`"', '"`UNIQ--vote-00000F1F-QINU`"'
'"`UNIQ--vote-00000F40-QINU`"', '"`UNIQ--vote-00000F41-QINU`"', '"`UNIQ--vote-00000F42-QINU`"', '"`UNIQ--vote-00000F43-QINU`"', '"`UNIQ--vote-00000F44-QINU`"'
'"`UNIQ--vote-00000F5C-QINU`"', '"`UNIQ--vote-00000F5D-QINU`"'
'"`UNIQ--vote-00000F78-QINU`"', '"`UNIQ--vote-00000F79-QINU`"', '"`UNIQ--vote-00000F7A-QINU`"'
'"`UNIQ--vote-00000F98-QINU`"', '"`UNIQ--vote-00000F99-QINU`"', '"`UNIQ--vote-00000F9A-QINU`"', '"`UNIQ--vote-00000F9B-QINU`"'
'"`UNIQ--vote-00000FB3-QINU`"', '''adjunctive only''' (does not treat the underlying infection)
'"`UNIQ--vote-00000FCF-QINU`"', '"`UNIQ--vote-00000FD0-QINU`"', '"`UNIQ--vote-00000FD1-QINU`"'
'"`UNIQ--vote-00000FF3-QINU`"', '"`UNIQ--vote-00000FF4-QINU`"', '"`UNIQ--vote-00000FF5-QINU`"', '"`UNIQ--vote-00000FF6-QINU`"', '"`UNIQ--vote-00000FF7-QINU`"', '"`UNIQ--vote-00000FF8-QINU`"'
'"`UNIQ--vote-00001016-QINU`"', '"`UNIQ--vote-00001017-QINU`"', '"`UNIQ--vote-00001018-QINU`"', '"`UNIQ--vote-00001019-QINU`"'
'"`UNIQ--vote-00001035-QINU`"', '"`UNIQ--vote-00001036-QINU`"', '"`UNIQ--vote-00001037-QINU`"'
'"`UNIQ--vote-0000104E-QINU`"', '"`UNIQ--vote-0000104F-QINU`"'
'"`UNIQ--vote-00001069-QINU`"', '"`UNIQ--vote-0000106A-QINU`"'
'"`UNIQ--vote-0000108C-QINU`"', '"`UNIQ--vote-0000108D-QINU`"', '"`UNIQ--vote-0000108E-QINU`"', '"`UNIQ--vote-0000108F-QINU`"', '"`UNIQ--vote-00001090-QINU`"', '"`UNIQ--vote-00001091-QINU`"'
'"`UNIQ--vote-000010AF-QINU`"', '"`UNIQ--vote-000010B0-QINU`"', '"`UNIQ--vote-000010B1-QINU`"', '"`UNIQ--vote-000010B2-QINU`"'
'"`UNIQ--vote-000010CE-QINU`"', '"`UNIQ--vote-000010CF-QINU`"', '"`UNIQ--vote-000010D0-QINU`"'
'"`UNIQ--vote-0000111D-QINU`"', '"`UNIQ--vote-0000111E-QINU`"'
'"`UNIQ--vote-0000113C-QINU`"', '"`UNIQ--vote-0000113D-QINU`"', '"`UNIQ--vote-0000113E-QINU`"'
'"`UNIQ--vote-0000115F-QINU`"', '"`UNIQ--vote-00001160-QINU`"', '"`UNIQ--vote-00001161-QINU`"', '"`UNIQ--vote-00001162-QINU`"', '"`UNIQ--vote-00001163-QINU`"'
'"`UNIQ--vote-0000117B-QINU`"'
'"`UNIQ--vote-00001199-QINU`"', '"`UNIQ--vote-0000119A-QINU`"', '"`UNIQ--vote-0000119B-QINU`"'
'"`UNIQ--vote-000011BA-QINU`"', '"`UNIQ--vote-000011BB-QINU`"', '"`UNIQ--vote-000011BC-QINU`"', '"`UNIQ--vote-000011BD-QINU`"'
'"`UNIQ--vote-000011D7-QINU`"', '"`UNIQ--vote-000011D8-QINU`"'
'"`UNIQ--vote-000011F6-QINU`"', '"`UNIQ--vote-000011F7-QINU`"', '"`UNIQ--vote-000011F8-QINU`"'
'"`UNIQ--vote-00001215-QINU`"', '"`UNIQ--vote-00001216-QINU`"', '"`UNIQ--vote-00001217-QINU`"'
'"`UNIQ--vote-00001235-QINU`"', '"`UNIQ--vote-00001236-QINU`"', '"`UNIQ--vote-00001237-QINU`"', '"`UNIQ--vote-00001238-QINU`"'
'"`UNIQ--vote-0000124D-QINU`"', '"`UNIQ--vote-0000124E-QINU`"', '"`UNIQ--vote-0000124F-QINU`"'
'"`UNIQ--vote-0000126B-QINU`"', '"`UNIQ--vote-0000126C-QINU`"', '"`UNIQ--vote-0000126D-QINU`"'
'"`UNIQ--vote-00001286-QINU`"'
'"`UNIQ--vote-0000129E-QINU`"'
'"`UNIQ--vote-000012B7-QINU`"', '"`UNIQ--vote-000012B8-QINU`"', '"`UNIQ--vote-000012B9-QINU`"', '"`UNIQ--vote-000012BA-QINU`"', '"`UNIQ--vote-000012BB-QINU`"'
'"`UNIQ--vote-000012CE-QINU`"', '"`UNIQ--vote-000012CF-QINU`"', '"`UNIQ--vote-000012D0-QINU`"'
'"`UNIQ--vote-000012E5-QINU`"', '"`UNIQ--vote-000012E6-QINU`"', '"`UNIQ--vote-000012E7-QINU`"', '"`UNIQ--vote-000012E8-QINU`"'
'"`UNIQ--vote-00001303-QINU`"', '"`UNIQ--vote-00001304-QINU`"', '"`UNIQ--vote-00001305-QINU`"', '"`UNIQ--vote-00001306-QINU`"', '"`UNIQ--vote-00001307-QINU`"', '"`UNIQ--vote-00001308-QINU`"', '"`UNIQ--vote-00001309-QINU`"'
'"`UNIQ--vote-0000131A-QINU`"', '"`UNIQ--vote-0000131B-QINU`"'
'"`UNIQ--vote-0000132E-QINU`"', '"`UNIQ--vote-0000132F-QINU`"', '"`UNIQ--vote-00001330-QINU`"'
'"`UNIQ--vote-00001341-QINU`"', '"`UNIQ--vote-00001342-QINU`"'
'"`UNIQ--vote-00001358-QINU`"', '"`UNIQ--vote-00001359-QINU`"'
'"`UNIQ--vote-00001372-QINU`"', '"`UNIQ--vote-00001373-QINU`"'
'"`UNIQ--vote-00001393-QINU`"', '"`UNIQ--vote-00001394-QINU`"', '"`UNIQ--vote-00001395-QINU`"', '"`UNIQ--vote-00001396-QINU`"', '"`UNIQ--vote-00001397-QINU`"'
'"`UNIQ--vote-000013B3-QINU`"', '"`UNIQ--vote-000013B4-QINU`"', '"`UNIQ--vote-000013B5-QINU`"'
'"`UNIQ--vote-000013CF-QINU`"', '"`UNIQ--vote-000013D0-QINU`"'
'"`UNIQ--vote-000013F0-QINU`"', '"`UNIQ--vote-000013F1-QINU`"', '"`UNIQ--vote-000013F2-QINU`"', '"`UNIQ--vote-000013F3-QINU`"', '"`UNIQ--vote-000013F4-QINU`"'
'"`UNIQ--vote-00001414-QINU`"', '"`UNIQ--vote-00001415-QINU`"', '"`UNIQ--vote-00001416-QINU`"', '"`UNIQ--vote-00001417-QINU`"', '"`UNIQ--vote-00001418-QINU`"'
'"`UNIQ--vote-0000143C-QINU`"', '"`UNIQ--vote-0000143D-QINU`"', '"`UNIQ--vote-0000143E-QINU`"', '"`UNIQ--vote-0000143F-QINU`"', '"`UNIQ--vote-00001440-QINU`"', '"`UNIQ--vote-00001441-QINU`"'
'"`UNIQ--vote-0000145E-QINU`"', '"`UNIQ--vote-0000145F-QINU`"', '"`UNIQ--vote-00001460-QINU`"'
'"`UNIQ--vote-0000147C-QINU`"', '"`UNIQ--vote-0000147D-QINU`"', '"`UNIQ--vote-0000147E-QINU`"'
'"`UNIQ--vote-0000149A-QINU`"', '"`UNIQ--vote-0000149B-QINU`"', '"`UNIQ--vote-0000149C-QINU`"'
'"`UNIQ--vote-000014BE-QINU`"', '"`UNIQ--vote-000014BF-QINU`"', '"`UNIQ--vote-000014C0-QINU`"', '"`UNIQ--vote-000014C1-QINU`"', '"`UNIQ--vote-000014C2-QINU`"'
'"`UNIQ--vote-000014DF-QINU`"', '"`UNIQ--vote-000014E0-QINU`"', '"`UNIQ--vote-000014E1-QINU`"'
'"`UNIQ--vote-000014F9-QINU`"'
'"`UNIQ--vote-00001515-QINU`"', '"`UNIQ--vote-00001516-QINU`"'
'"`UNIQ--vote-0000152F-QINU`"'
'"`UNIQ--vote-0000154B-QINU`"', '"`UNIQ--vote-0000154C-QINU`"'
'"`UNIQ--vote-00001567-QINU`"'
'"`UNIQ--vote-00001582-QINU`"'
'"`UNIQ--vote-0000159D-QINU`"', '"`UNIQ--vote-0000159E-QINU`"'
'"`UNIQ--vote-000015B6-QINU`"'
'"`UNIQ--vote-000015D0-QINU`"'
Search
starting dose:
5 mg PO once daily (no renal dose adjustment, unlike sitagliptin) (1)
preparations:
5 mg tablets; combination with metformin (1)
fda max:
(Click arrow to add another value)
None
·
Indication-specific
·
40 mg/d
·
10 mg/d
·
20 mg/d
·
80 mg/d
·
10 mg/d (adults)
·
100 mg/d
·
4 g/d
·
400 mg/d
·
40 mg/d typical; up to 240 mg/d for Zollinger-Ellison
· 5 mg/d ·
50 mg/d
·
600 mg/d
·
No fixed ceiling; titrate to clinical effect and tolerability with CDC opioid prescribing guidance constraints on morphine-milligram-equivalent (MME) totals
·
No fixed maximum; titrated to TSH target
·
TID per eye
·
Titrated to glucose; no fixed ceiling
·
Titrated to glucose; no fixed maximum
·
'''20 mg/day in adults >60 years''' per FDA's 2011-2012 QT-prolongation warning; 40 mg/day in adults ≤60
Other values:
'''4.5 mg/kg (without epinephrine), 7 mg/kg (with epinephrine)''' for infiltration; serum level monitoring required for prolonged IV antiarrhythmic use
0.5 mg/d
0.8 mg/d (rarely needed)
1 capsule BID (40 mg DXM / 20 mg quinidine per day)
1 drop per eye q8-12h
1 drop/eye/day (more frequent dosing reduces efficacy)
1 g/d (oral); 6 g/d (IV)
1 mg/d
1 mg/d typical Rx; higher in specific indications
1.8 mg in any 1-hour period (acute gout); 1.2 mg/d (prophylaxis with renal/hepatic impairment); much lower with strong CYP3A4 or P-gp inhibitors
1.8 mg/day SC (Victoza, T2DM)'"`UNIQ--ref-00000185-QINU`"' · 3.0 mg/day SC (Saxenda, obesity)'"`UNIQ--ref-00000186-QINU`"'
10 mg BID for the first 7 days of acute VTE; otherwise 5 mg BID
10 mg per 24 h
10 mg/d (5 mg if severe renal or moderate hepatic impairment, or strong CYP3A4 inhibitors)
10 mg/day (IR); 12.5 mg/day (CR)
10 mg/day (anxiety, oral)
10 mg/kg q2w
10 µg twice daily (Byetta)'"`UNIQ--ref-000000E7-QINU`"' · 2 mg once weekly (Bydureon BCise)'"`UNIQ--ref-000000E8-QINU`"'
100 mcg/d typical
100 mg/d (ED); 20 mg TID (PAH)
100 mg/d (rarely used)
100 mg/day (adult)
100 mg/day (adult); 1.4 mg/kg/day or 100 mg total (pediatric, whichever lower)
100 mg/day (vertigo)
100-200 mg/day depending on indication
1000 mg/d (osteoarthritis); 1200 mg/d (rheumatoid arthritis)
12 inhalations/d (rescue); higher for severe exacerbation under monitoring
12 puffs MDI/d typical; nebulized 2000 mcg/d
120 mg/d (ER); IR not for chronic hypertension
120 mg/day (IV/IM); 40 mg/day (oral); '''5-day maximum total combined therapy''' to mitigate the GI bleeding, AKI, and platelet dysfunction risks
1200 mg/day (adult seizures); 1600 mg/day (bipolar mania)
140 mg/month
1400 mg q4w
15 mg/day (oral); 30 mg IV once daily (Anjeso)
15 mg/wk SC'"`UNIQ--ref-000002FE-QINU`"''"`UNIQ--ref-000002FF-QINU`"'
150 mg/d
150 mg/d (treatment)
150 mg/day (oral); use lowest effective dose for shortest duration per FDA NSAID class guidance
150 mg/day; therapeutic plasma-level monitoring recommended (target 50-150 ng/mL window)
1500 mg/day (Rx); 660 mg/24h (OTC, without provider direction)
16 mg/d (8 mg/d OTC)
16 mg/d (IR); 8 mg/d (XL)
16 mg/day (schizophrenia, adult); 6 mg/day (bipolar maintenance, autism irritability)
160 mg/d (Zollinger-Ellison); 80 mg/d for routine indications
160 mg/d (rarely tolerated due to anticholinergic effects)
1600 mg/day (theoretical seizure dosing); practical use 400 mg/day for seizures, 100-200 mg/day for migraine prophylaxis
18 mg olanzapine / 75 mg fluoxetine per day
180 mg/d (adults)
195 units/treatment for chronic migraine; max varies by problem
2 g/d (Niaspan); higher off-label use historical
2 g/d typical
2 g/day (seizures); typically much lower for essential tremor
2 mg/wk SC (Ozempic)'"`UNIQ--ref-0000024B-QINU`"' · 2.4 mg/wk SC (Wegovy)'"`UNIQ--ref-0000024C-QINU`"' · 14 mg PO daily (Rybelsus)'"`UNIQ--ref-0000024D-QINU`"'
2 sprays/nostril BID
2 tablets per 24 hours; ≤4 days per month to avoid medicine-overuse headache
2 tablets/day (dextromethorphan 90 mg / bupropion 210 mg)
2.4 g/d
2.4 mg/day (HTN, IR); 0.4 mg/day (ADHD, Kapvay)
20 mg/d (ED, PRN); 5 mg/d (daily / BPH); 40 mg/d (PAH)
20 mg/d (hypertension); 10 mg/d (other indications typical)
20 mg/day (IR); 28 mg/day (XR)
20 mg/day (adult); 10 mg/day in elderly and in hepatic impairment
20 mg/day (oral)
20 mg/day (seizures); commonly limited to 4 mg/day for anxiety in current practice
200 mg/d
200 mg/d (100 mg/d if on CYP3A4 inhibitors)
200 mg/d typical practical ceiling
200 mg/day (oral); 12 mg/day (SC); 40 mg/day (nasal spray); 44 mg/day (Onzetra)
200 mg/day (typical adult oral)
2000 mg/d
225 mg/day outpatient (XR); 375 mg/day inpatient (IR divided TID); 75 mg/day in moderate hepatic impairment
23 mg/day
24 mg/day (Parkinson disease); 4 mg/day (restless legs syndrome)
24/6 mg/d (most labels)
240 mg loading + 120 mg/month for migraine; 300 mg/month for cluster
240 mg/d (mononitrate ER); 160 mg/d (dinitrate)
240 mg/day
2400 mg/day (adult)
2400 mg/day (oral); 300 mg total per IV bolus dosing series
25 mg/d
25 mg/day (ADHD per Desoxyn label); 15 mg/day (obesity, short-term, per Desoxyn label)
250 mg/d
2550 mg/d (IR); 2000 mg/d (ER)
28/10 mg/d
290 mcg/d
3 g/d (zoster)
3 g/d typical; higher in severe infections under specialist guidance
30 mg/24 hours
30 mg/d (XL) typical
30 mg/d (acute VTE first 21 days as 15 mg BID); otherwise 20 mg/d
30 mg/d for short-term use
30 mg/day (IR or ER)
30 mg/day (adult schizophrenia); 15 mg/day (MDD adjunct)
300 mg/d
300 mg/d typical practical limit (toxicity rises sharply above)
300 mg/day (IR or CR)
300 mg/day (depression, hospitalized); 150 mg/day outpatient; 6 mg/day for insomnia
300 mg/day (historical hospitalized inpatient depression); 150 mg/day outpatient typical ceiling
300 mg/day (oral)
300 mg/quarter
3000 mg/day
32 mg naltrexone / 360 mg bupropion per day
32 mg/day adult; weight-based pediatric ceiling
320 mg/d (hypertension); 320 mg/d (HF)
3200 mg/day (Rx); 1200 mg/day (OTC, without provider direction)
34 mg/d
35.6 mg/d
36 mg/day in three divided doses; single dose maximum 16 mg
360 mg/day
3600 mg/day; off-label doses higher are common but bioavailability saturates well below this
37.5 mg/d
4 L per procedure (standard-volume products)
4 g/d (rarely tolerated due to GI effects)
4 g/d in healthy adults; 3 g/d conservative limit; 2 g/d in cirrhosis or chronic alcohol use
4 g/d typical
4 mg/d (schizophrenia); 3 mg/d (AD agitation); 3 mg/d (MDD adjunct)
4% topical; limit duration of use
4.5 mg/day (Parkinson disease); 0.5 mg/day (restless legs syndrome)
4.5 mg/wk SC'"`UNIQ--ref-00000055-QINU`"'
4.8 g/d (IV severe infection)
40 mg every week (selected indications); otherwise 40 mg every other week
40 mg/d (IR; doses >15 mg given as divided BID); 20 mg/d (XL)
40 mg/d (rarely needed; 40 mg restricted to patients not at goal on 20 mg)
40 mg/d standard; 80 mg/d restricted to patients tolerating 80 mg for ≥12 months without myopathy (post-SEARCH 2011 FDA restriction)
40 mg/d typical; up to 360 mg/d for Zollinger-Ellison
40 mg/day (oral, anxiety)
400 mg/d (acute primary aldosteronism diagnosis); 100-200 mg/d typical chronic
400 mg/d (pediatric); 600 mg/d (adult)
400 mg/d (rarely used)
400 mg/d typical maintenance; weight-adjusted ceiling per ophthalmology guidance
400 mg/day (IR, adult); 300 mg/day (ER); 300 mg/day in elderly >75 years
400 mg/day (bipolar monotherapy); 700 mg/day (epilepsy with enzyme-inducing comedication)
400 mg/day for chronic indications; higher for short-term acute pain
400 mg/day outpatient; 600 mg/day inpatient
400 mg/day theoretical; in practice rarely exceeds 200 mg/day
4000 mg/day (analgesic)
42 mg/d
420 mg/month
45 mg/d
45 mg/day
450 mg/day; doses above this raise seizure risk steeply
5 mg/d (adults)
50 g/week (cream/ointment); 2-week continuous limit; 4-week maximum cumulative
50 mg BID in heart failure (or once-daily equivalent CR); 25 mg BID in hypertension
50 mg/d (hypertension); up to 200 mg/d (edema)
50 mg/d × 14 d
50 mg/day (IR); 62.5 mg/day (CR); 60 mg/day (OCD)
50 mg/day (no efficacy benefit shown for higher doses despite the 100 mg strength being available)
500 mg/d (typical regimen); single 2 g for Zmax; 2 g for select STIs
6 capsules/d (300 mg butalbital, 1950 mg acetaminophen, 240 mg caffeine)
6 capsules/d (300 mg butalbital, 1950 mg aspirin, 240 mg caffeine)
6 mg/d (psychosis/mania); 3 mg/d (depression adjunct)
60 mg/d typical
60 mg/day
60 mg/day (oral, hypertension); 0.5% BID (ophthalmic)
60 mg/kg/d (typically up to 3000 mg/d)
600 mg/d typical practical ceiling in heart failure
600 mg/day (seizures); 450 mg/day (fibromyalgia and neuropathic pain)
640 mg/d (HTN); 240 mg/d (migraine)
675 mg/quarter
7 mg/day in children and adolescents; weight-based ceiling (~0.12 mg/kg/day) applies in smaller patients
70 mg/day
70 mg/week treatment; 40 mg/d for 6 months in Paget's
75 mg per dose; one dose per 24 hours (acute); one dose every other day (preventive)
75 mg/d maintenance (loading doses are single events)
750 mg/d
8 g/day (oral, short-term load); 6 g/day (chronic)
8 mg/d
8 tablets/d (300 mg tramadol / 2600 mg acetaminophen); 5-day duration limit per label
80 mg/d (40 mg/d if combined with diltiazem, verapamil, danazol; lower limits with various interactions)
80 mg/day oral (higher off-label)
800 mg/d
800 mg/d (rarely needed)
800 mg/d (severe invasive disease)
800 mg/day
84 mg per session
9 g/night
90 mg BID (acute year); 60 mg BID (chronic post-MI)
Acetaminophen 4 g/d absolute (3 g/d conservative); oxycodone titrated to effect
Acetaminophen 4 g/d absolute; codeine 240-360 mg/d typical practical limit
Aspirin GI/bleeding-limited; oxycodone titrated to effect
BID topical; once daily nail lacquer
Formulation-dependent
Formulation-specific (e.g., 145 mg/d Tricor, 200 mg/d Lipofen)
Formulation-specific; ~4.8 g/d typical maximum oral
ICS 880 mcg/d (asthma); intranasal 200 mcg/d
ICS ~1280 mcg/d; intranasal 256 mcg/d; Entocort 9 mg/d standard
IV peripheral 10 mEq/h (40 mEq/L); IV central 20 mEq/h with cardiac monitoring; PO single doses generally ≤40 mEq
IV: monitored by levels (trough <1 mg/L for extended-interval; <2 mg/L for traditional)
Indication-dependent; 200-400 mg/d oral typical
Indication-specific; ACLS no fixed cumulative ceiling
Indication-specific; HE may require high-volume dosing
Indication-specific; bowel prep regimens reach 4 L cumulative
Indication-specific; high-dose IV regimens for encephalitis or disseminated disease
Indication-specific; lowest effective dose for shortest duration is the WHI-era standard
Indication-specific; renal clearance limits tolerable cumulative dosing
Indication-specific; titrated to effect
Intranasal 200 mcg/d (adults); inhaled 880 mcg/d
Limit to 48 hours of use to avoid hemolysis and methemoglobinemia
Limit topical to 10-day courses to reduce resistance pressure
N/A (never approved)
N/A (no current medical indication)
No fixed maximum; cumulative-dose toxicity drives all chronic decisions
No fixed maximum; titrated to INR target
No fixed maximum; titrated to clinical endpoints
No fixed maximum; titrated to pH and bicarbonate level; chronic high oral doses cause metabolic alkalosis and volume overload
No fixed maximum; titrated; sodium correction rate in chronic hyponatremia must not exceed 8-10 mEq/L per 24 hours to avoid osmotic demyelination
No strict ceiling for water-soluble vitamin; UL not set
No strict ceiling; water-soluble vitamin, low toxicity
No strict; Institute of Medicine UL 4,000 IU/d in adults for chronic use
Not FDA-approved; clinical-trial protocols use up to 30 mg in adult investigational dosing
Not formally established (dietary supplement); doses above ~3-5 mg show no additional efficacy but increase next-day sedation risk
Not strictly fixed; long-term Upper Limit ~4,000 IU/d in adults (Institute of Medicine)
Not yet approved
Once daily (Pataday 0.7%); BID (other ophthalmic)
One dose per day
One drop per eye per day
Oral maintenance 400 mg/d typical; higher in refractory cases
Per formulation
Rheumatologic ~25 mg/week; oncology indication-specific
Single 200-400 mcg/kg per dose for systemic indications
Single 60-hour course
Single doses ≤16 mg (FDA 2012 advisory withdrew the 32 mg single IV dose for QT-prolongation risk); 24-32 mg/d divided
Titrated to glucose
Titrated; risk of hypercalcemia is the limiting factor
Topical: BID; troche: 5×/day
Topical: nightly; oral APL: 45 mg/m²/d
Topical: nightly; systemic: regimen-specific
Topical: per formulation; oral supplement age-dependent
Topical: regimen-specific; oral: 400 mg/d in remaining specialty indications
Transplant: regimen-specific
UL 1000 mg (~1500 IU natural)/d in adults; routinely exceeded in older AREDS-1 trials
UL 2000 mg/d in adults
Withdrawn 2024
XR = 40 or 60 mg/d; IR = 40 or 60 mg/d'"`UNIQ--ref-00000567-QINU`"'
~10 mg/d typical
~1500 mg/d (oral); 1200 mg/d (IV)
~200 mg elemental iron/d typical practical limit
~200 mg/d for most indications; higher doses for severe infections
~2500 mg elemental/d combined diet + supplements (chronic; UL)
~4 g/d (severe systemic infection)
~480 mg/d (oral) for cardiovascular indications; higher off-label for cluster
~480 mg/d (oral); IV per protocol
~500 mg/d typical
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routes:
Oral (1)
onset:
Postprandial glucose effect within days; HbA1c by 12 weeks (1)
duration:
24 hours (1)
halflife:
~12 hours (effective); terminal much longer'"`UNIQ--ref-0000117C-QINU`"' (1)
bioavailability:
~30% (oral)'"`UNIQ--ref-0000117D-QINU`"' (1)
pregnancy:
Limited data; switch to insulin where feasible.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)
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