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Medicines > generic : 2-FDCK or Azithromycin & fda max: 500 mg/d (typical regimen); single 2 g for Zmax; 2 g for select STIs

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generic: (Click arrow to add another value)
brand:
Zithromax, Z-Pak, Zmax (1)
classes:
[[:Category:Azalides|Azalide]] (1) · [[:Category:Macrolide_antibiotics|Macrolide antibiotic]] (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-000003F6-QINU`"', '"`UNIQ--vote-000003F7-QINU`"', '"`UNIQ--vote-000003F8-QINU`"', '"`UNIQ--vote-000003F9-QINU`"', '"`UNIQ--vote-000003FA-QINU`"', '"`UNIQ--vote-000003FB-QINU`"' (1)
starting dose:
500 mg PO day 1, then 250 mg PO daily days 2-5 (Z-Pak); 1 g PO single dose for chlamydia; pediatric dosing 10 mg/kg day 1, 5 mg/kg days 2-5 (1)
preparations:
250 mg, 500 mg, 600 mg tablets; 100, 200 mg/5 mL suspension; 2 g ER suspension (Zmax); 500 mg IV (1)
fda max: (Click arrow to add another value)
routes:
IV (1) · Oral (1)
onset:
Clinical improvement within 24-72 hours (1)
duration:
Tissue half-life supports once-daily and post-treatment effect (1)
halflife:
~68 hours (terminal; reflects deep tissue accumulation, much longer than plasma)'"`UNIQ--ref-000003FC-QINU`"' (1)
bioavailability:
~37% (oral; food reduces absorption modestly)'"`UNIQ--ref-000003FD-QINU`"' (1)
pregnancy:
Generally considered safe; commonly used in pregnancy when macrolide indicated.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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