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Drilldown/Medicines

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Medicines > generic : Clopidogrel or Codeine & fda max: 75 mg/d maintenance (loading doses are single events)

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generic: (Click arrow to add another value)
brand:
Plavix (1)
classes:
[[:Category:Antiplatelet_agents|Antiplatelet agent]] (1) · [[:Category:P2Y12_inhibitors|P2Y12 receptor inhibitor]] (1) · [[:Category:Thienopyridines|Thienopyridine]] (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-000002C0-QINU`"', '"`UNIQ--vote-000002C1-QINU`"', '"`UNIQ--vote-000002C2-QINU`"', '"`UNIQ--vote-000002C3-QINU`"' (1)
starting dose:
75 mg PO once daily for maintenance; 300-600 mg PO loading dose in ACS or before PCI (1)
preparations:
75 mg, 300 mg tablets (1)
fda max: (Click arrow to add another value)
routes:
Oral (1)
onset:
Antiplatelet effect within 2 hours of a loading dose; steady-state at 5-7 days of maintenance dosing (1)
duration:
5-7 days (platelet lifespan; irreversible receptor binding) (1)
halflife:
~6 hours (parent); active metabolite very short-lived but produces irreversible platelet effect'"`UNIQ--ref-000002C4-QINU`"' (1)
bioavailability:
~50% (oral)'"`UNIQ--ref-000002C5-QINU`"' (1)
pregnancy:
Limited data; weigh against alternatives (aspirin) where feasible.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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