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Medicines > fda max: Intranasal 200 mcg/d (adults); inhaled 880 mcg/d & routes : IV/IM (Buprenex). Oral swallowed: very low bioavailability due to first-pass; not therapeutic. or topical

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generic:
Mometasone furoate (1)
brand:
Nasonex (intranasal), Asmanex (inhaled), Elocon (topical), Sinuva (sinus implant); with formoterol as Dulera (1)
classes:
[[:Category:Corticosteroids|Corticosteroid]] (1) · [[:Category:Glucocorticoids|Glucocorticoid]] (1) · [[:Category:Inhaled_corticosteroids|Inhaled corticosteroid (ICS)]] (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-00000F98-QINU`"', '"`UNIQ--vote-00000F99-QINU`"', '"`UNIQ--vote-00000F9A-QINU`"', '"`UNIQ--vote-00000F9B-QINU`"' (1)
starting dose:
Intranasal Nasonex 2 sprays/nostril daily (50 mcg/spray); inhaled Asmanex 220 mcg DPI 1-2 inhalations daily/BID; topical Elocon 0.1% cream daily (1)
preparations:
Nasonex 50 mcg/actuation intranasal; Asmanex HFA MDI 100/200 mcg; Asmanex Twisthaler DPI 110/220 mcg; Elocon 0.1% cream/ointment/lotion; Sinuva sinus implant; Dulera (with formoterol) (1)
fda max: (Click arrow to add another value)
routes: (Click arrow to add another value)
onset:
Intranasal: symptom relief 12-24 hours; inhaled: bronchial effect 1-2 weeks (1)
duration:
24 hours (1)
halflife:
~5 hours (plasma)'"`UNIQ--ref-00000F9C-QINU`"' (1)
bioavailability:
Intranasal: <1% systemic; inhaled lung deposition with extensive first-pass clearance'"`UNIQ--ref-00000F9D-QINU`"' (1)
pregnancy:
Intranasal long considered acceptable; widely used in obstetric rhinitis.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
OTC (Nasonex 24HR) and [[USLegal:Prescription only|Rx-only]] (other forms) in US (1)

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