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Drilldown: Medicines

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Medicines > fda max: ~1500 mg/d (oral); 1200 mg/d (IV) & routes : Intravenous (continuous infusion in a REMS-certified facility) or Topical ophthalmic

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generic:
Ciprofloxacin (1)
brand:
Cipro, Cipro XR, Ciloxan (ophthalmic) (1)
classes:
[[:Category:Antibacterials|Antibacterial]] (1) · [[:Category:Fluoroquinolones|Fluoroquinolone antibiotic]] (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-00000932-QINU`"', '"`UNIQ--vote-00000933-QINU`"', '"`UNIQ--vote-00000934-QINU`"', '"`UNIQ--vote-00000935-QINU`"', '"`UNIQ--vote-00000936-QINU`"', '"`UNIQ--vote-00000937-QINU`"' (1)
starting dose:
500-750 mg PO BID; 400 mg IV q8-12h (1)
preparations:
250, 500, 750 mg IR tablets; 500, 1000 mg ER tablets (XR); 250, 500 mg/5 mL oral suspension; 200, 400 mg IV; 0.3% ophthalmic solution and ointment; 0.2% otic (1)
fda max: (Click arrow to add another value)
routes: (Click arrow to add another value)
onset:
Hours (1)
duration:
8-12 hours (1)
halflife:
4 hours'"`UNIQ--ref-00000938-QINU`"' (1)
bioavailability:
~70% (oral; reduced by divalent cations — antacids, iron, calcium, dairy)'"`UNIQ--ref-00000939-QINU`"' (1)
pregnancy:
'''Avoid in pregnancy where alternatives exist''' (animal cartilage toxicity; class-wide concern); use only when benefit clearly outweighs.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
None (1)

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