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Drilldown: Medicines

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Medicines > fda max: ~200 mg/d for most indications; higher doses for severe infections & onset : Day 3 of dosing in trials; sustained through day 45 or Hours

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generic:
Doxycycline (1)
brand:
Vibramycin, Doryx, Oracea, Adoxa, Monodox, Acticlate (1)
classes:
[[:Category:Bacteriostatic_antibiotics|Bacteriostatic antibiotic]] (1) · [[:Category:Tetracycline_antibiotics|Tetracycline antibiotic]] (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-00000475-QINU`"', '"`UNIQ--vote-00000476-QINU`"', '"`UNIQ--vote-00000477-QINU`"', '"`UNIQ--vote-00000478-QINU`"', '"`UNIQ--vote-00000479-QINU`"', '"`UNIQ--vote-0000047A-QINU`"', '"`UNIQ--vote-0000047B-QINU`"', '"`UNIQ--vote-0000047C-QINU`"' (1)
starting dose:
100 mg PO BID; rickettsial 200 mg/d; doxy-PEP 200 mg within 72 hours after condomless sex (1)
preparations:
50 mg, 75 mg, 100 mg, 150 mg tablets and capsules; delayed-release; suspension; IV (1)
fda max: (Click arrow to add another value)
routes:
IV (1) · Oral (1)
onset: (Click arrow to add another value)
duration:
12 hours (1)
halflife:
16-22 hours'"`UNIQ--ref-0000047D-QINU`"' (1)
bioavailability:
~95% (oral; reduced by dairy, antacids, iron via divalent-cation chelation, though less than for tetracycline itself)'"`UNIQ--ref-0000047E-QINU`"' (1)
pregnancy:
None (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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