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Medicines > generic: Metronidazole & fda max: ~4 g/d (severe systemic infection)

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generic: (Click arrow to add another value)
brand:
Flagyl, Metrocream, Metrogel, Metrogel-Vaginal, Noritate (1)
classes:
[[:Category:Antibacterials|Antibacterial (anaerobic)]] (1) · [[:Category:Antiprotozoals|Antiprotozoal]] (1) · [[:Category:Nitroimidazoles|Nitroimidazole antibiotic]] (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-00000BE3-QINU`"', '"`UNIQ--vote-00000BE4-QINU`"', '"`UNIQ--vote-00000BE5-QINU`"', '"`UNIQ--vote-00000BE6-QINU`"', '"`UNIQ--vote-00000BE7-QINU`"', '"`UNIQ--vote-00000BE8-QINU`"', '"`UNIQ--vote-00000BE9-QINU`"', '"`UNIQ--vote-00000BEA-QINU`"' (1)
starting dose:
500 mg PO TID × 7-10 days (most indications); 2 g single dose for trichomoniasis; 500 mg IV q8h for severe anaerobic infection; rectal 1 g BID (1)
preparations:
250, 500 mg tablets; 750 mg ER; 500 mg/100 mL IV; 0.75-1% topical gel/cream; 0.75% vaginal gel; suppository (1)
fda max: (Click arrow to add another value)
routes:
IV (1) · Oral (1) · topical (1) · vaginal (1)
onset:
Hours (1)
duration:
8-12 hours (1)
halflife:
6-8 hours'"`UNIQ--ref-00000BEB-QINU`"' (1)
bioavailability:
~80% (oral)'"`UNIQ--ref-00000BEC-QINU`"' (1)
pregnancy:
Generally considered safe after the first trimester; first-trimester use weighed against indication.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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