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Medicines > generic : 1B-LSD or 25B-NBOH or Methadone

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generic: (Click arrow to add another value)
brand:
None (2) · Dolophine, Methadose, Diskets (oral dispersible tablets for OTPs) (1)
classes:
Classic Psychedelic (2) · Lysergamide (1) · Phenethylamine (1) · Research material (2) · [[:Category:NMDA antagonists|NMDA receptor antagonist]] (1) · [[:Category:Opioid analgesics|Opioid analgesic (full mu-agonist)]] (1) · [[:Category:Schedule II controlled substances|Schedule II controlled substance]] (1)
mechanism:
None (1) · Potent 5-HT2A agonist (1) · Prodrug of LSD; 5-HT2A agonist (1)
uses:
None (2) · '"`UNIQ--vote-0000004C-QINU`"', '"`UNIQ--vote-0000004D-QINU`"', '"`UNIQ--vote-0000004E-QINU`"' (1)
starting dose:
None (3)
preparations:
None (2) · Tablets 5, 10, 40 mg (40 mg dispersible restricted to OTPs); oral concentrate 10 mg/mL; oral solution 1, 2, 10 mg/mL; injection 10 mg/mL (1)
fda max:
None (2) · No formal hard ceiling; in MOUD maintenance, doses typically remain at or below 120 mg/day with higher doses reserved for documented under-treatment after careful clinical assessment (1)
routes:
None (2) · IM (1) · IV (1) · Oral (primary) (1) · SC (1) · sublingual; rectal off-label (1)
onset:
None (2) · Oral analgesic effect 30-60 minutes; opioid-withdrawal suppression 30 minutes (oral); IV ~10 minutes (1)
duration:
None (2) · Analgesic effect 4-8 hours (much shorter than half-life would suggest, due to receptor kinetics); MOUD effect (opioid withdrawal suppression) 24-36 hours per single daily dose (1)
halflife:
None (3)
bioavailability:
None (2) · ~70-85% (oral, high relative to other opioids) (1)
pregnancy:
None (3)
legal:
None (3)

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