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Drilldown: Medicines

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Medicines > generic : 2-AI or 2-FDCK or Sildenafil

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generic: (Click arrow to add another value)
brand:
None (2) · Viagra, Revatio (1)
classes:
Dissociative (1) · PDE5 Inhibitor (1) · Research material (2) · Stimulant (1)
mechanism:
Alpha-methylated amphetamine analogue; norepinephrine releasing agent (1) · NMDA antagonist; fluorinated ketamine analogue (1) · Selective inhibitor of phosphodiesterase type 5 (PDE5), preventing cGMP breakdown in vascular smooth muscle. In the corpus cavernosum, potentiates the NO/cGMP cascade triggered by sexual stimulation. (1)
uses:
None (2) · '"`UNIQ--vote-00000705-QINU`"', '"`UNIQ--vote-00000706-QINU`"' (1)
starting dose:
None (2) · 50 mg ~1 h before sexual activity (ED); 20 mg TID (PAH) (1)
preparations:
None (2) · 25, 50, 100 mg tabs (Viagra); 20 mg tabs and 10 mg/mL oral suspension (Revatio) (1)
fda max:
None (2) · 100 mg/d (ED); 20 mg TID (PAH) (1)
routes:
None (2) · IV (Revatio) (1) · Oral (1)
onset:
None (2) · 30–60 min (1)
duration:
None (2) · ~4 h (1)
halflife:
None (2) · ~4 h (1)
bioavailability:
None (2) · ~40% (1)
pregnancy:
None (2) · Category B (1)
legal:
None (2) · Rx-only in US (1)

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