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Medicines > generic : 2-AI or 2-FMA or Cetirizine

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generic: (Click arrow to add another value)
brand:
None (2) · Zyrtec, Zyrtec-D (1)
classes:
Amphetamine (1) · Research material (2) · Stimulant (2) · [[:Category:Antihistamines|Antihistamine]] (1) · [[:Category:H1_receptor_antagonists|Histamine H1 receptor antagonist (second-generation)]] (1)
mechanism:
Alpha-methylated amphetamine analogue; norepinephrine releasing agent (1) · Monoamine releasing agent (1) · '"`UNIQ--vote-00000391-QINU`"' Minimal CYP metabolism; mostly renally cleared unchanged. Cetirizine is the active racemate; levocetirizine is the active R-enantiomer marketed separately'"`UNIQ--ref-00000392-QINU`"'. (1)
uses:
None (2) · '"`UNIQ--vote-00000393-QINU`"', '"`UNIQ--vote-00000394-QINU`"', '"`UNIQ--vote-00000395-QINU`"' (1)
starting dose:
None (2) · 10 mg PO once daily (5 mg in older adults or if sedation occurs) (1)
preparations:
None (2) · 5 mg, 10 mg tablets; 5 mg, 10 mg chewables; 1 mg/mL oral syrup; OTC (1)
fda max:
None (2) · 10 mg/d (adults) (1)
routes:
None (2) · Oral (1)
onset:
None (2) · 30-60 minutes (1)
duration:
None (2) · 24 hours (1)
halflife:
None (2) · 8-10 hours (longer in elderly and renal impairment)'"`UNIQ--ref-00000396-QINU`"' (1)
bioavailability:
None (2) · High (oral); not significantly affected by food'"`UNIQ--ref-00000397-QINU`"' (1)
pregnancy:
None (2) · Generally considered safe; widely used. Levocetirizine (the R-enantiomer) is an alternative with similar safety.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
None (2) · OTC in US (1)

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