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Drilldown: Medicines

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Medicines > generic : 2-AI or 25B-NBOMe or Nebivolol

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generic: (Click arrow to add another value)
brand:
None (2) · Bystolic (1)
classes:
Beta Blocker (1) · Cardioselective (β1) + vasodilator (1) · Classic Psychedelic (1) · Phenethylamine (1) · Research material (2) · Stimulant (1)
mechanism:
Alpha-methylated amphetamine analogue; norepinephrine releasing agent (1) · Potent 5-HT2A agonist; no oral activity (1) · The d-enantiomer is a highly β1-selective antagonist; the l-enantiomer triggers endothelial nitric-oxide–mediated vasodilation. Unique among beta blockers for this NO mechanism. (1)
uses:
None (2) · '"`UNIQ--vote-0000059D-QINU`"' (1)
starting dose:
None (2) · 5 mg daily (1)
preparations:
None (2) · 2.5, 5, 10, 20 mg tabs (1)
fda max:
None (2) · 40 mg/d (1)
routes:
None (2) · Oral (1)
onset:
None (2) · 1–2 h (1)
duration:
None (2) · 24 h (1)
halflife:
None (2) · ~10 h (CYP2D6 extensive metabolizers); up to 31 h (poor metabolizers) (1)
bioavailability:
None (2) · ~12% (extensive metabolizers); ~96% (poor metabolizers) (1)
pregnancy:
None (2) · Category C (1)
legal:
None (2) · Rx-only in US (1)

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