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Drilldown: Medicines

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Medicines > generic : 2-AI or 25B-NBOMe or Prazosin

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generic: (Click arrow to add another value)
brand:
None (2) · Minipress (1)
classes:
Alpha-1 Adrenergic Antagonist (1) · Classic Psychedelic (1) · Phenethylamine (1) · Research material (2) · Stimulant (1)
mechanism:
Alpha-methylated amphetamine analogue; norepinephrine releasing agent (1) · Potent 5-HT2A agonist; no oral activity (1) · Selective alpha-1 adrenergic receptor antagonist. Lowers peripheral vascular resistance via vasodilation; in the CNS, blunts noradrenergic hyperarousal thought to drive trauma-related nightmares. (1)
uses:
None (2) · '"`UNIQ--vote-000005D0-QINU`"', '"`UNIQ--vote-000005D1-QINU`"', '"`UNIQ--vote-000005D2-QINU`"' (1)
starting dose:
None (2) · 1 mg at bedtime (PTSD nightmares); 1 mg BID–TID (HTN) (1)
preparations:
None (2) · 1, 2, 5 mg caps (1)
fda max:
None (2) · 40 mg/d (1)
routes:
None (2) · Oral (1)
onset:
None (2) · 30–90 min (1)
duration:
None (2) · 6–8 h (1)
halflife:
None (2) · 2–3 h (1)
bioavailability:
None (2) · ~60% (1)
pregnancy:
None (2) · Category C (1)
legal:
None (2) · Rx-only in US (1)

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