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Medicines > generic : 2-AI or 25C-NBOH or Ergocalciferol (vitamin D2)

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generic: (Click arrow to add another value)
brand:
None (2) · Drisdol, Calcidol; also many OTC preparations (1)
classes:
Classic Psychedelic (1) · Phenethylamine (1) · Research material (2) · Stimulant (1) · [[:Category:Fat-soluble_vitamins|Fat-soluble vitamin]] (1) · [[:Category:Vitamin_D_analogs|Vitamin D analog]] (1)
mechanism:
Alpha-methylated amphetamine analogue; norepinephrine releasing agent (1) · Potent 5-HT2A agonist (1) · '"`UNIQ--vote-0000032A-QINU`"' D3 (cholecalciferol) is more potent at raising serum 25(OH)D per dose; D2 remains widely prescribed in the US Rx 50,000 IU formulation'"`UNIQ--ref-0000032B-QINU`"'. (1)
uses:
None (2) · '"`UNIQ--vote-0000032C-QINU`"', '"`UNIQ--vote-0000032D-QINU`"', '"`UNIQ--vote-0000032E-QINU`"', '"`UNIQ--vote-0000032F-QINU`"' (1)
starting dose:
None (2) · Deficiency: 50,000 IU PO weekly for 8-12 weeks, then maintenance 800-2,000 IU/day; maintenance OTC dosing typically 800-2,000 IU/d (1)
preparations:
None (2) · 50,000 IU capsules (Rx); 8,000 IU/mL oral solution (Rx); 400-5,000 IU OTC tablets and softgels (1)
fda max:
None (2) · Not strictly fixed; long-term Upper Limit ~4,000 IU/d in adults (Institute of Medicine) (1)
routes:
None (2) · Oral (1)
onset:
None (2) · Days to weeks to raise 25(OH)D; clinical effect on bone over months (1)
duration:
None (2) · Long; fat-soluble, stored in adipose (1)
halflife:
None (2) · ~24 hours (parent); ~15 days (25(OH)D); 25(OH)D stores persist for months'"`UNIQ--ref-00000330-QINU`"' (1)
bioavailability:
None (2) · ~75% (oral; fat-soluble, absorption requires intact biliary/lipid digestion)'"`UNIQ--ref-00000331-QINU`"' (1)
pregnancy:
None (2) · Safe at replacement doses; deficiency is itself a risk in pregnancy and lactation.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
None (2) · OTC (low-dose) and [[USLegal:Prescription only|Rx-only]] (50,000 IU and concentrated solutions) in US (1)

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