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Drilldown: Medicines

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Medicines > generic : 2-AI or 2C-B or Flibanserin

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generic: (Click arrow to add another value)
brand:
None (1) · Addyi (1) · Nexus, Eroxan (historical, late-1980s through mid-1990s) (1)
classes:
2C-x series (1) · Multimodal serotonergic; HSDD treatment (1) · Phenethylamine (1) · Psychedelic (1) · Research material (1) · Stimulant (1)
mechanism:
5-HT1A agonist, 5-HT2A antagonist, with weaker activity at D4 and other receptors. Net effect involves enhanced prefrontal dopaminergic/noradrenergic tone with decreased serotonergic inhibition of sexual desire. (1) · 5-HT2A partial agonist (1) · Alpha-methylated amphetamine analogue; norepinephrine releasing agent (1)
uses:
None (2) · '"`UNIQ--vote-000002C1-QINU`"' (1)
starting dose:
None (2) · 100 mg at bedtime daily (1)
preparations:
None (2) · 100 mg tabs (1)
fda max:
None (2) · 100 mg/d (1)
routes:
None (1) · insufflated (1) · Oral (2) · PR (1)
onset:
None (1) · 45-75 min (oral) (1) · Effects accumulate over weeks; assess at 8 weeks (1)
duration:
None (1) · 4-8 h (1) · Continuous daily dosing (1)
halflife:
None (1) · Not well characterized (1) · ~11 h (1)
bioavailability:
None (1) · Not well characterized (1) · ~33% (1)
pregnancy:
None (1) · Not established (1) · Not indicated; pregnancy effects unknown (1)
legal:
None (1) · Rx-only in US (REMS program) (1) · [[USLegal:DEA Schedule I|Schedule I]] (United States) (1)

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