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: 2-AI

or Insulin glargine

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None (1) · Lantus, Basaglar, Semglee, Toujeo (U-300) (1)

Research material (1) · Stimulant (1) · [[:Category:Basal_insulins|Basal insulin]] (1) · [[:Category:Insulins|Insulin]] (1) · [[:Category:Long-acting_insulins|Long-acting insulin analog]] (1)

Alpha-methylated amphetamine analogue; norepinephrine releasing agent (1) · '"`UNIQ--vote-00000237-QINU`"' Binds the same insulin receptor as endogenous insulin with comparable mitogenic-to-metabolic ratio; provides basal hepatic glucose suppression and peripheral glucose uptake without prandial peaks'"`UNIQ--ref-00000238-QINU`"'. (1)

None (1) · '"`UNIQ--vote-00000239-QINU`"', '"`UNIQ--vote-0000023A-QINU`"' (1)

None (1) · ~10 units SC at the same time daily, or 0.1-0.2 units/kg/d; titrate by fasting glucose (1)

None (1) · 100 U/mL (Lantus, Basaglar, Semglee) vials and pens; 300 U/mL (Toujeo) pens (1)

None (1) · Titrated to glucose; no fixed ceiling (1)

None (1) · Subcutaneous (never IV; not for use in insulin pumps) (1)

None (1) · 1-2 hours (1)

None (1) · ~24 hours per dose (peakless profile by design) (1)

None (1) · ~12 hours apparent (functional duration ~24 hours due to depot release kinetics)'"`UNIQ--ref-0000023B-QINU`"' (1)

None (1) · ~100% from subcutaneous depot (by definition of the route) (1)

None (1) · Insulin is the preferred glucose-lowering therapy in pregnancy; glargine has reassuring observational data, though NPH and detemir remain the traditional choices.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1)

None (1) · [[USLegal:Prescription only|Rx-only]] in US (1)

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Insulin Glargine

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