Drilldown: Medicines

None · Codeine · 1,4-Butanediol · 1B-LSD · 1cP-LSD · 1P-LSD · 1V-LSD · 2-AI · 2-FA · 2-FDCK · 2-FMA · 25B-NBOH · 25B-NBOMe · 25C-NBOH · 25C-NBOMe · 25I-NBOH · 25I-NBOMe · 25N-NBOMe · 2C-B · 2C-B-FLY

Other values:

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None (2) · (multiple, generic dominant) (1) · Stendra (1)

Amphetamine (1) · Analgesic (2) · Opioid (2) · PDE5 Inhibitor (1) · Prodrug (1) · Research material (1) · Stimulant (1)

Monoamine releasing agent (1) · Mu-opioid receptor agonist; prodrug (metabolized to morphine) (1) · Prodrug; converted to [[Morphine|morphine]] by [[Enzyme:CYP2D6|CYP2D6]] for analgesic action. (1) · Selective inhibitor of phosphodiesterase type 5 (PDE5); increases cGMP in cavernous smooth muscle, producing erection in response to sexual stimulation. (1)

None (2) · Mild to moderate pain; cough suppression (low-dose). (1) · '"`UNIQ--vote-00000040-QINU`"' (1)

None (2) · 100 mg ~15 min before sexual activity (1) · Adult: 15–60 mg every 4 hours as needed. (1)

None (2) · 50, 100, 200 mg tabs (1) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1)

None (2) · 200 mg/d (100 mg/d if on CYP3A4 inhibitors) (1) · 360 mg/day (1)

None (2) · Oral (1) · PO (only formulation marketed in the US). (1)

None (2) · 30–60 min (PO) (1) · ~15 min (fastest of the PDE5 inhibitors) (1)

None (2) · 4–6 h (1) · 4–6 hours (1)

None (2) · 2.5–3 hours (1) · ~5 h (1)

None (2) · Rapid absorption; absolute bioavailability not formally established (1) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1)

None (2) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1) · Category C (not relevant; not used in women) (1)

None (2) · Rx-only in US (1) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1)