Jump to content

Drilldown: Medicines

Pharmacopedia
BrowseCategoriesLog in

Choose a table:


Medicines > generic : 2-FA or Codeine or Vitamin E (α-tocopherol; mixed natural and synthetic forms)

Use the filters below to narrow your results.

generic: (Click arrow to add another value)
brand:
None (2) · (multiple, generic dominant) (1) · Generic; many OTC formulations (1)
classes:
Amphetamine (1) · Analgesic (2) · Opioid (2) · Prodrug (1) · Research material (1) · Stimulant (1) · [[:Category:Antioxidants|Antioxidant]] (1) · [[:Category:Fat-soluble_vitamins|Fat-soluble vitamin]] (1) · [[:Category:Vitamins|Vitamin]] (1)
mechanism:
None (1) · Monoamine releasing agent (1) · Mu-opioid receptor agonist; prodrug (metabolized to morphine) (1) · Prodrug; converted to [[Morphine|morphine]] by [[Enzyme:CYP2D6|CYP2D6]] for analgesic action. (1)
uses:
None (2) · Mild to moderate pain; cough suppression (low-dose). (1) · '"`UNIQ--vote-000012CE-QINU`"', '"`UNIQ--vote-000012CF-QINU`"', '"`UNIQ--vote-000012D0-QINU`"' (1)
starting dose:
None (2) · Adult: 15–60 mg every 4 hours as needed. (1) · Replacement: 15-30 mg (22.5-45 IU) daily; NASH: 800 IU daily; AREDS-2: 400 IU daily (in combination formula) (1)
preparations:
None (2) · 100, 200, 400 IU softgels and capsules; many proprietary OTC blends; combined formulations (AREDS-2) (1) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1)
fda max:
None (2) · 360 mg/day (1) · UL 1000 mg (~1500 IU natural)/d in adults; routinely exceeded in older AREDS-1 trials (1)
routes:
None (2) · Oral (1) · PO (only formulation marketed in the US). (1)
onset:
None (2) · 30–60 min (PO) (1) · Days to weeks for tissue saturation (1)
duration:
None (2) · 4–6 hours (1) · Weeks (fat-soluble) (1)
halflife:
None (2) · 2.5–3 hours (1) · ~3-4 days plasma; adipose tissue stores last months (1)
bioavailability:
None (2) · High with fat-containing meal; reduced in malabsorption (1) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1)
pregnancy:
None (2) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1) · Safe at replacement doses; high-dose use generally avoided.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
None (2) · OTC in US (1) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1)

Showing below up to 4 results in range #1 to #4.

View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)


View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)

Retrieved from "https://pharmacopedia.wiki/p/Special:Drilldown/Medicines"