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Medicines (732)

Medicines > generic

: 2-FDCK

or 2-FMA

or Linaclotide

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None (2) · Linzess (1)

Amphetamine (1) · Dissociative (1) · Research material (2) · Stimulant (1) · [[:Category:Guanylate_cyclase_C_agonists|Guanylate cyclase-C agonist]] (1) · [[:Category:IBS_treatments|IBS-C treatment]] (1)

Monoamine releasing agent (1) · NMDA antagonist; fluorinated ketamine analogue (1) · '"`UNIQ--vote-00001197-QINU`"' Extracellular cGMP separately activates submucosal sensory afferents in a way that reduces visceral pain perception, distinguishing linaclotide from purely osmotic laxatives in IBS-C. Diarrhea is the dose-limiting effect'"`UNIQ--ref-00001198-QINU`"'. (1)

None (2) · '"`UNIQ--vote-00001199-QINU`"', '"`UNIQ--vote-0000119A-QINU`"', '"`UNIQ--vote-0000119B-QINU`"' (1)

None (2) · 145 mcg PO once daily for chronic idiopathic constipation; 290 mcg daily for IBS-C; pediatric 72 mcg daily (1)

None (2) · 72, 145, 290 mcg capsules (1)

None (2) · 290 mcg/d (1)

None (2) · Oral (1)

None (2) · Bowel movement within 1 week; abdominal pain improvement over weeks (1)

None (2) · 24 hours (1)

None (2) · Not meaningfully described (negligible systemic absorption — the drug acts locally and is degraded in the GI tract)'"`UNIQ--ref-0000119C-QINU`"' (1)

None (2) · Negligible systemic absorption'"`UNIQ--ref-0000119D-QINU`"' (1)

None (2) · Limited data; minimal systemic absorption likely renders fetal risk low.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1)

None (2) · [[USLegal:Prescription only|Rx-only]] in US. Carries a '''Boxed Warning''' contraindicating use in children <2 years (lethal dehydration in animal studies)'"`UNIQ--ref-0000119E-QINU`"' (1)

Showing below up to 3 results in range #1 to #3.

2

2-FDCK

2-FMA

L

Linaclotide

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