Drilldown: Medicines

None · Codeine · 1,4-Butanediol · 1B-LSD · 1cP-LSD · 1P-LSD · 1V-LSD · 2-AI · 2-FA · 2-FDCK · 2-FMA · 25B-NBOH · 25B-NBOMe · 25C-NBOH · 25C-NBOMe · 25I-NBOH · 25I-NBOMe · 25N-NBOMe · 2C-B · 2C-B-FLY

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None (2) · (multiple, generic dominant) (1) · Wormwood, absinthe, la Fée Verte, the Green Muse (1)

Analgesic (2) · Dissociative (1) · Opioid (2) · Plant Medicine (1) · Prodrug (1) · Research material (1) · Rhapsodica (1)

Active principle is thujone, a GABA-A antagonist (the opposite of most CNS depressants). Also present in cooking sage (''Salvia officinalis''), tansy, and ''Thuja'' cedars. (1) · Mu-opioid receptor agonist; prodrug (metabolized to morphine) (1) · NMDA antagonist; fluorinated ketamine analogue (1) · Prodrug; converted to [[Morphine|morphine]] by [[Enzyme:CYP2D6|CYP2D6]] for analgesic action. (1)

None (2) · Mild to moderate pain; cough suppression (low-dose). (1) · '"`UNIQ--vote-00000008-QINU`"', '"`UNIQ--vote-00000009-QINU`"' (1)

None (2) · A measured pour of absinthe diluted 5:1 with cold water over sugar (the louche ritual) (1) · Adult: 15–60 mg every 4 hours as needed. (1)

None (2) · Dried leaves; absinthe liqueur (120–160 proof, with hyssop, lemon balm, fennel, anise, sometimes Acorus calamus) (1) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1)

None (3) · 360 mg/day (1)

None (2) · Oral (1) · PO (only formulation marketed in the US). (1)

None (3) · 30–60 min (PO) (1)

None (3) · 4–6 hours (1)

None (3) · 2.5–3 hours (1)

None (3) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1)

None (3) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1)

None (2) · Currently legal in most jurisdictions with thujone limits (1) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1)