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Medicines > generic : 2-FMA or 25B-NBOMe or Oxycodone (hydrochloride)

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generic: (Click arrow to add another value)
brand:
None (2) · OxyContin (ER), Roxicodone (IR), Oxaydo (IR abuse-deterrent), Xtampza ER (abuse-deterrent ER) (1)
classes:
Amphetamine (1) · Classic Psychedelic (1) · Phenethylamine (1) · Research material (2) · Stimulant (1) · [[:Category:Analgesics|Analgesic]] (1) · [[:Category:Opioid analgesics|Opioid analgesic (semi-synthetic)]] (1) · [[:Category:Schedule II controlled substances|Schedule II controlled substance]] (1)
mechanism:
None (1) · Monoamine releasing agent (1) · Potent 5-HT2A agonist; no oral activity (1)
uses:
None (2) · '"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"', '"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"' (1)
starting dose:
None (2) · IR opioid-naive: 5-10 mg PO every 4-6 hours as needed. ER opioid-naive: '''10 mg PO every 12 hours (lowest available)'''; titrate slowly to clinical effect (1)
preparations:
None (2) · IR tablets 5, 7.5, 10, 15, 20, 30 mg; IR oral solution 5 mg/5 mL; concentrated solution 20 mg/mL; OxyContin ER tablets 10, 15, 20, 30, 40, 60, 80 mg; Xtampza ER capsules (1)
fda max:
None (2) · No fixed ceiling; titrate to clinical effect and tolerability with CDC opioid prescribing guidance constraints on morphine-milligram-equivalent (MME) totals (1)
routes:
None (2) · Oral (1)
onset:
None (2) · 10-30 minutes (IR) (1)
duration:
None (2) · 4-6 hours (IR); 12 hours (ER) (1)
halflife:
None (2) · 3-5 hours (IR); 4.5 hours (ER)'"`UNIQ--ref-0000001D-QINU`"' (1)
bioavailability:
None (2) · ~60-87% (oral; high and more consistent than codeine or hydrocodone, making efficacy less CYP2D6-genotype-dependent)'"`UNIQ--ref-0000001E-QINU`"' (1)
pregnancy:
None (2) · Chronic third-trimester exposure produces neonatal opioid withdrawal syndrome and respiratory depression at delivery.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
None (2) · [[USLegal:Schedule II|Schedule II controlled substance]] in US'"`UNIQ--ref-0000001F-QINU`"' (1)

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