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Drilldown: Medicines

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Medicines > generic : 2-FMA or Codeine or Phentermine

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generic: (Click arrow to add another value)
brand:
None (2) · (multiple, generic dominant) (1) · Adipex-P, Lomaira (low-dose); with topiramate as Qsymia (1)
classes:
Amphetamine (1) · Analgesic (2) · Opioid (2) · Prodrug (1) · Research material (1) · Stimulant (1) · [[:Category:Anorectics|Anorectic (appetite suppressant)]] (1) · [[:Category:Schedule_IV_controlled_substances|Schedule IV controlled substance]] (1) · [[:Category:Sympathomimetics|Sympathomimetic]] (1)
mechanism:
None (1) · Monoamine releasing agent (1) · Mu-opioid receptor agonist; prodrug (metabolized to morphine) (1) · Prodrug; converted to [[Morphine|morphine]] by [[Enzyme:CYP2D6|CYP2D6]] for analgesic action. (1)
uses:
None (2) · Mild to moderate pain; cough suppression (low-dose). (1) · '"`UNIQ--vote-0000129E-QINU`"' (1)
starting dose:
None (2) · 15-37.5 mg PO once daily before breakfast or 1-2 hours after; Lomaira 8 mg TID (1) · Adult: 15–60 mg every 4 hours as needed. (1)
preparations:
None (2) · 15, 30, 37.5 mg capsules/tablets; 8 mg Lomaira (1) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1)
fda max:
None (2) · 360 mg/day (1) · 37.5 mg/d (1)
routes:
None (2) · Oral (1) · PO (only formulation marketed in the US). (1)
onset:
None (2) · 30–60 min (PO) (1) · Appetite suppression within hours; weight loss over weeks-months (1)
duration:
None (2) · 4–6 hours (1) · ~12-14 hours (1)
halflife:
None (2) · 2.5–3 hours (1) · ~25 hours'"`UNIQ--ref-0000129F-QINU`"' (1)
bioavailability:
None (2) · High (oral)'"`UNIQ--ref-000012A0-QINU`"' (1) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1)
pregnancy:
None (2) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1) · Contraindicated in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
None (3) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1)

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