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Medicines (732)

Medicines > generic

: 25B-NBOMe

or 2C-B

or Dextromethorphan / Quinidine

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None (1) · Nexus, Eroxan (historical, late-1980s through mid-1990s) (1) · Nuedexta (1)

None (1) · 2C-x series (1) · Classic Psychedelic (1) · Phenethylamine (2) · Psychedelic (1) · Research material (1)

5-HT2A partial agonist (1) · Potent 5-HT2A agonist; no oral activity (1) · '"`UNIQ--vote-00001580-QINU`"' First FDA-approved treatment for PBA. The 10 mg quinidine daily dose is far below antiarrhythmic levels but sufficient to nearly fully inhibit CYP2D6, the basis of the combination's pharmacokinetic rationale'"`UNIQ--ref-00001581-QINU`"'. (1)

None (2) · '"`UNIQ--vote-00001582-QINU`"' (1)

None (2) · 1 capsule (20/10 mg dextromethorphan/quinidine) PO once daily × 7 days, then 1 capsule BID (1)

None (2) · 20 mg dextromethorphan HBr / 10 mg quinidine sulfate capsules (1)

None (2) · 1 capsule BID (40 mg DXM / 20 mg quinidine per day) (1)

None (1) · insufflated (1) · Oral (2) · PR (1)

None (1) · 45-75 min (oral) (1) · PBA episode reduction within 1-2 weeks (1)

None (1) · 12 hours (1) · 4-8 h (1)

None (1) · Dextromethorphan substantially prolonged by quinidine's CYP2D6 inhibition (typical extensive metabolizers see ~10× higher AUC); quinidine ~6-8 hours'"`UNIQ--ref-00001583-QINU`"' (1) · Not well characterized (1)

None (1) · Increased substantially via CYP2D6 inhibition'"`UNIQ--ref-00001584-QINU`"' (1) · Not well characterized (1)

None (1) · Limited data; quinidine has been used in pregnancy as antiarrhythmic.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1) · Not established (1)

None (1) · [[USLegal:DEA Schedule I|Schedule I]] (United States) (1) · [[USLegal:Prescription only|Rx-only]] in US. Caution with QT-prolonging medicines (quinidine itself is class IA antiarrhythmic, and the dose here, though sub-antiarrhythmic, still contributes to QT)'"`UNIQ--ref-00001585-QINU`"' (1)

Showing below up to 3 results in range #1 to #3.

2

25B-NBOMe

2C-B

N

Nuedexta

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