Drilldown: Medicines

None · Codeine · 1,4-Butanediol · 1B-LSD · 1cP-LSD · 1P-LSD · 1V-LSD · 2-AI · 2-FA · 2-FDCK · 2-FMA · 25B-NBOH · 25B-NBOMe · 25C-NBOH · 25C-NBOMe · 25I-NBOH · 25I-NBOMe · 25N-NBOMe · 2C-B · 2C-B-FLY

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None (2) · ''Myristica fragrans''. Mace (the fruit aril) (1) · (multiple, generic dominant) (1)

Analgesic (2) · Classic Psychedelic (1) · Empathogenica (1) · Opioid (2) · Phenethylamine (1) · Plant Med (1) · Prodrug (1) · Research material (1)

Active oils are myristicin, elemicin, and safrole, phenethylamine precursors that may be aminated in vivo to MMDA, TMA, and MDA respectively (Shulgin's 'essential amphetamines' hypothesis). (1) · Mu-opioid receptor agonist; prodrug (metabolized to morphine) (1) · Potent 5-HT2A agonist (1) · Prodrug; converted to [[Morphine|morphine]] by [[Enzyme:CYP2D6|CYP2D6]] for analgesic action. (1)

None (2) · Mild to moderate pain; cough suppression (low-dose). (1) · '"`UNIQ--vote-00000006-QINU`"' (1)

None (2) · 0.5–1 oz (10–30 g) ground for psychoactive effect; far smaller for culinary use (1) · Adult: 15–60 mg every 4 hours as needed. (1)

None (2) · Ground dried seed (nutmeg) or fruit aril (mace); occasionally infused (1) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1)

None (3) · 360 mg/day (1)

None (2) · Oral (1) · PO (only formulation marketed in the US). (1)

None (2) · 30–60 min (PO) (1) · Slow, 2–6 h (1)

None (2) · 12–24 h or longer (1) · 4–6 hours (1)

None (3) · 2.5–3 hours (1)

None (3) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1)

None (3) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1)

None (3) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1)