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Medicines > generic : 25C-NBOMe or Irbesartan

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generic: (Click arrow to add another value)
brand:
None (1) · Avapro (1)
classes:
Classic Psychedelic (1) · Phenethylamine (1) · Research material (1) · [[:Category:Angiotensin_receptor_blockers|Angiotensin receptor blocker (ARB)]] (1) · [[:Category:Antihypertensives|Antihypertensive]] (1)
mechanism:
Potent 5-HT2A agonist (1) · '"`UNIQ--vote-0000083E-QINU`"' CYP2C9 substrate; no clinically active metabolites. The IDNT trial established renoprotection in diabetic nephropathy independent of BP lowering, contributing to the ARB class indication in T2DM with proteinuria'"`UNIQ--ref-0000083F-QINU`"'. (1)
uses:
None (1) · '"`UNIQ--vote-00000840-QINU`"', '"`UNIQ--vote-00000841-QINU`"' (1)
starting dose:
None (1) · 150 mg PO once daily; titrate to 300 mg if needed (1)
preparations:
None (1) · 75, 150, 300 mg tablets (1)
fda max:
None (1) · 300 mg/d (1)
routes:
None (1) · Oral (1)
onset:
None (1) · BP effect within 1-2 weeks (1)
duration:
None (1) · 24 hours (1)
halflife:
None (1) · 11-15 hours'"`UNIQ--ref-00000842-QINU`"' (1)
bioavailability:
None (1) · 60-80% (oral; not significantly affected by food)'"`UNIQ--ref-00000843-QINU`"' (1)
pregnancy:
None (1) · '''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, hypocalvaria, hypotension. Stop on detection'"`UNIQ--ref-00000844-QINU`"' (1)
legal:
None (1) · [[USLegal:Prescription only|Rx-only]] in US (1)

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