Drilldown: Medicines

None · Codeine · 1,4-Butanediol · 1B-LSD · 1cP-LSD · 1P-LSD · 1V-LSD · 2-AI · 2-FA · 2-FDCK · 2-FMA · 25B-NBOH · 25B-NBOMe · 25C-NBOH · 25C-NBOMe · 25I-NBOH · 25I-NBOMe · 25N-NBOMe · 2C-B · 2C-B-FLY

Other values:

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None (2) · (multiple, generic dominant) (1) · Bystolic (1)

Analgesic (2) · Beta Blocker (1) · Cardioselective (β1) + vasodilator (1) · Classic Psychedelic (1) · Opioid (2) · Phenethylamine (1) · Prodrug (1) · Research material (1)

Mu-opioid receptor agonist; prodrug (metabolized to morphine) (1) · Potent 5-HT2A agonist (1) · Prodrug; converted to [[Morphine|morphine]] by [[Enzyme:CYP2D6|CYP2D6]] for analgesic action. (1) · The d-enantiomer is a highly β1-selective antagonist; the l-enantiomer triggers endothelial nitric-oxide–mediated vasodilation. Unique among beta blockers for this NO mechanism. (1)

None (2) · Mild to moderate pain; cough suppression (low-dose). (1) · '"`UNIQ--vote-0000059D-QINU`"' (1)

None (2) · 5 mg daily (1) · Adult: 15–60 mg every 4 hours as needed. (1)

None (2) · 2.5, 5, 10, 20 mg tabs (1) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1)

None (2) · 360 mg/day (1) · 40 mg/d (1)

None (2) · Oral (1) · PO (only formulation marketed in the US). (1)

None (2) · 1–2 h (1) · 30–60 min (PO) (1)

None (2) · 24 h (1) · 4–6 hours (1)

None (2) · 2.5–3 hours (1) · ~10 h (CYP2D6 extensive metabolizers); up to 31 h (poor metabolizers) (1)

None (2) · ~12% (extensive metabolizers); ~96% (poor metabolizers) (1) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1)

None (2) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1) · Category C (1)

None (2) · Rx-only in US (1) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1)