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Medicines > generic: Coffee & halflife : Psilocin: ~2-3 h; psilocybin itself is a prodrug, dephosphorylated within minutes of absorption or ~5 h (caffeine)

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generic: (Click arrow to add another value)
brand:
''Coffea arabica'', ''Coffea canephora'' (robusta) (1)
classes:
Caffeine plant (1) · Excitantia (1) · Plant Medicine (1) · Xanthine (1)
mechanism:
Caffeine is a non-selective adenosine A1/A2A receptor antagonist; also weak PDE inhibition. Beans contain theobromine (3,7-DMX) and theophylline (1,3-DMX) in smaller amounts. (1)
uses:
'"`UNIQ--vote-000000CF-QINU`"', '"`UNIQ--vote-000000D0-QINU`"', '"`UNIQ--vote-000000D1-QINU`"' (1)
starting dose:
One cup (~80–145 mg caffeine for brewed; 60–100 mg for instant) (1)
preparations:
Roasted beans, ground; brewed (drip, French press, espresso, cold brew, percolated) (1)
fda max:
None (1)
routes:
Oral (1)
onset:
~15–30 min (1)
duration:
3–5 h (subjective) (1)
halflife: (Click arrow to add another value)
bioavailability:
~99% (caffeine) (1)
pregnancy:
Limit to <200 mg/d (~2 cups brewed) (1)
legal:
Unrestricted (food) (1)

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