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Drilldown: Medicines

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Medicines (732)

Medicines > generic: Epinephrine (adrenaline)

& routes: IM

& onset: IM: 5-10 minutes; IV: seconds; nebulized: 5-10 minutes

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EpiPen, EpiPen Jr, Auvi-Q, Adrenaclick, Symjepi; many generic (1)

[[:Category:Catecholamines|Catecholamine]] (1) · [[:Category:Inotropes|Inotrope]] (1) · [[:Category:Sympathomimetics|Sympathomimetic]] (1) · [[:Category:Vasopressors|Vasopressor]] (1)

'"`UNIQ--vote-00000E4A-QINU`"' The narrow safe-bolus window for IV use (sharp risk of arrhythmia, hypertensive emergency, intracerebral hemorrhage) is why anaphylaxis dosing is '''IM, not IV''', outside critical care'"`UNIQ--ref-00000E4B-QINU`"'. (1)

'"`UNIQ--vote-00000E4C-QINU`"', '"`UNIQ--vote-00000E4D-QINU`"', '"`UNIQ--vote-00000E4E-QINU`"', '"`UNIQ--vote-00000E4F-QINU`"', '"`UNIQ--vote-00000E50-QINU`"', '"`UNIQ--vote-00000E51-QINU`"' (1)

Anaphylaxis IM 0.3-0.5 mg (adult) into lateral thigh, repeat q5-15 minutes prn; pediatric 0.01 mg/kg IM (max 0.3 mg, max 0.5 mg in adolescents); cardiac arrest 1 mg IV/IO q3-5 minutes; severe asthma neb 0.1 mg/kg up to 5 mg; never IV bolus for anaphylaxis outside critical care (1)

Auto-injectors 0.15 mg (Jr/pediatric), 0.3 mg (adult); 1 mg/mL (1:1,000) ampules for IM/SC use; 0.1 mg/mL (1:10,000) for IV use; 2.25% racemic nebulizer (1)

Indication-specific; ACLS no fixed cumulative ceiling (1)

5-15 minutes (1)

~2 minutes'"`UNIQ--ref-00000E52-QINU`"' (1)

IM/SC ~100%; oral negligible (extensive first-pass and gut metabolism — hence the no-oral route)'"`UNIQ--ref-00000E53-QINU`"' (1)

Used in life-threatening obstetric anaphylaxis without hesitation; benefits clearly outweigh.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1)

[[USLegal:Prescription only|Rx-only]] in US (1)

Showing below up to 1 result in range #1 to #1.

E

Epinephrine

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