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Drilldown: Medicines

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Medicines > generic: Hydrochlorothiazide & routes: Oral & halflife: 6-15 hours'"`UNIQ--ref-0000013E-QINU`"'

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generic: (Click arrow to add another value)
brand:
Microzide; mostly prescribed generically (1)
classes:
[[:Category:Antihypertensives|Antihypertensive]] (1) · [[:Category:Thiazide_diuretics|Thiazide diuretic]] (1)
mechanism:
'"`UNIQ--vote-00000138-QINU`"' Decreases urinary calcium (used in stone prevention); raises serum uric acid, glucose, and lipids modestly; non-anion-gap hypokalemic metabolic alkalosis is the characteristic electrolyte pattern'"`UNIQ--ref-00000139-QINU`"'. (1)
uses:
'"`UNIQ--vote-0000013A-QINU`"', '"`UNIQ--vote-0000013B-QINU`"', '"`UNIQ--vote-0000013C-QINU`"', '"`UNIQ--vote-0000013D-QINU`"' (1)
starting dose:
12.5-25 mg PO once daily (1)
preparations:
12.5 mg capsules; 12.5, 25, 50 mg tablets (1)
fda max:
50 mg/d (hypertension); up to 200 mg/d (edema) (1)
routes: (Click arrow to add another value)
onset:
Diuresis at 2 hours; antihypertensive effect within days, max at 3-4 weeks (1)
duration:
6-12 hours (1)
halflife: (Click arrow to add another value)
bioavailability:
65-75% (oral)'"`UNIQ--ref-0000013F-QINU`"' (1)
pregnancy:
None (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)
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