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Choose a table:
Medicines (732)
Medicines
> generic:
Mescal Bean
&
uses:
'"`UNIQ--vote-00000006-QINU`"'
&
onset:
None
Use the filters below to narrow your results.
generic:
(Click arrow to add another value)
None
·
Codeine
·
1,4-Butanediol
·
1B-LSD
·
1cP-LSD
·
1P-LSD
·
1V-LSD
·
2-AI
·
2-FA
·
2-FDCK
·
2-FMA
·
25B-NBOH
·
25B-NBOMe
·
25C-NBOH
·
25C-NBOMe
·
25I-NBOH
·
25I-NBOMe
·
25N-NBOMe
·
2C-B
·
2C-B-FLY
Other values:
2C-C
2C-D
2C-E
2C-I
2C-P
2C-T-2
2C-T-7
3,4-CTMP
3-FA
3-FMA
3-HO-PCE
3-HO-PCP
3-MMC
3-MeO-PCE
3-MeO-PCP
4-AcO-DET
4-AcO-DMT
4-AcO-DiPT
4-AcO-MET
4-AcO-MiPT
4-FA
4-FMA
4-HO-DET
4-HO-DPT
4-HO-DiPT
4-HO-EPT
4-HO-MET
4-HO-MiPT
4-MeO-PCP
4F-EPH
4F-MPH
5,6-MDO-DMT
5-APB
5-HTP
5-MAPB
5-MeO-DALT
5-MeO-DMT
5-MeO-DiPT
5-MeO-MiPT
5F-AKB48
5F-PB-22
6-APB
6-APDB
7-Hydroxymitragynine
AB-FUBINACA
AL-LAD
ALD-52
APICA
Acacia confusa
Acamprosate
Acetaminophen (paracetamol, APAP)
Acetylfentanyl
Acyclovir
Adalimumab
Adrafinil
Agomelatine
Albuterol
Alendronate
Alfentanil
Allopurinol
Allylescaline
Almotriptan
Alprazolam
Amanita muscaria
Amantadine
Amiodarone
Amitriptyline (hydrochloride)
Amlodipine
Amobarbital
Amoxapine
Amoxicillin
Anadenanthera colubrina
Anadenanthera peregrina
Anastrozole
Aniracetam
Apixaban
Apomorphine
Aripiprazole
Armodafinil
Artemisia absinthium
Ascorbic acid (vitamin C)
Asenapine
Aspirin (acetylsalicylic acid; ASA)
Atenolol
Atogepant
Atomoxetine
Atorvastatin
Atropa belladonna
Atropine
Avanafil
Ayahuasca
Azelastine
Azithromycin
Baclofen
Baeocystin
Banisteriopsis caapi
Benazepril
Benzocaine
Benzonatate
Benztropine
Benzydamine
Betamethasone (valerate, dipropionate, sodium phosphate, acetate)
Betel
Bimatoprost
Biperiden
Bisacodyl
Bisoprolol
Black Drink
Blue lotus
Brimonidine
Brivaracetam
Bromantane
Bromazepam
Bromazolam
Bromo-DragonFLY
Bromocriptine
Brompheniramine
Brugmansia
Budesonide
Bufo alvarius
Bufotenin
Bumetanide
Bupivacaine
Buprenorphine
Buprenorphine / Naloxone
Bupropion
Bupropion / Naltrexone
Buspirone
Butalbital
Butalbital / Acetaminophen / Caffeine
Butalbital / Aspirin / Caffeine
Butorphanol
Butylone
Cabergoline
Caffeine
Calcitriol (1,25-dihydroxyvitamin D3)
Calcium (carbonate, citrate, gluconate, chloride salts)
Calea zacatechichi
Cannabidiol
Cannabigerol
Cannabinol
Carbamazepine
Carbidopa/levodopa
Carfentanil
Carisoprodol
Carvedilol
Cathinone
Cefdinir
Cefuroxime (axetil oral, sodium IV)
Celecoxib
Cenobamate
Cephalexin
Cetirizine
Chlordiazepoxide
Chlorhexidine gluconate (CHG)
Chloroform
Chlorpheniramine
Chlorpromazine
Chlorthalidone
Chlorzoxazone
Chocolate
Cholecalciferol (vitamin D3)
Ciclopirox
Ciprofloxacin
Citalopram
Clindamycin
Clobazam
Clobetasol propionate
Clomipramine
Clonazepam
Clonazolam
Clonidine
Clopidogrel
Clorazepate
Clotrimazole
Clozapine
Coca
Cocaine
Codeine / Acetaminophen
Coffee
Colchicine
Coluracetam
Curare
Cyanocobalamin (vitamin B12)
Cyclazodone
Cyclobenzaprine
Cyclosporine (ciclosporin)
Cyproheptadine (hydrochloride)
DET
DMT
DOB
DOC
DOI
DOM
DPT
Dapagliflozin
Datura
Delta-10-THC
Delta-8-THC
Deschloroetizolam
Deschloroketamine
Desflurane
Desipramine
Desomorphine
Desoxypipradrol
Desvenlafaxine (succinate)
Dexamethasone
Dexmedetomidine
Dexmethylphenidate
Dextroamphetamine
Dextromethorphan
Dextromethorphan / Quinidine
Dextropropoxyphene
Dextrorphan
DiPT
Diacetylmorphine
Diazepam
Diclazepam
Diclofenac (sodium, potassium, epolamine; multiple salt forms)
Dicyclomine
Diethyl ether
Dihydrocodeine
Dihydroergotamine
Diltiazem
Dimenhydrinate
Diphenhydramine (hydrochloride; citrate)
Diphenidine
Disulfiram
Docusate (sodium or calcium)
Donepezil
Dorzolamide
Doxazosin
Doxepin (hydrochloride)
Doxycycline
Doxylamine
Dronabinol
Droperidol
Dulaglutide
Duloxetine
Dutasteride
EPT
ETH-LAD
Eletriptan
Empagliflozin
Enalapril (and enalaprilat IV)
Entacapone
Ephedrine
Ephenidine
Ephylone
Epinephrine (adrenaline)
Ergocalciferol (vitamin D2)
Ergotamine
Erythromycin
Escaline
Escitalopram
Eslicarbazepine
Esmolol
Esomeprazole
Estazolam
Estradiol (17β-estradiol)
Eszopiclone
Ethcathinone
Ethchlorvynol
Ethosuximide
Ethylmorphine
Ethylone
Ethylphenidate
Eticyclidine
Etizolam
Etodolac
Etomidate
Evolocumab
Exenatide
Ezetimibe
F-Phenibut
Famotidine
Felbamate
Fenethylline
Fenfluramine
Fenofibrate
Fentanyl
Ferrous sulfate
Fexofenadine
Finasteride
Flecainide
Flibanserin
Flualprazolam
Flubromazepam
Flubromazolam
Fluconazole
Flunitrazepam
Flunitrazolam
Fluorouracil (5-FU)
Fluoxetine
Fluphenazine
Flurazepam
Fluticasone
Fluvoxamine (maleate)
Folic acid (folate, pteroylglutamic acid)
Fosphenytoin
Frovatriptan
Furosemide
GBL
GHB
Gabapentin
Gaboxadol
Galantamine
Glimepiride
Glipizide
Glutethimide
Guaifenesin
Guanfacine
Guarana
HHC
Haloperidol
Halothane
Harmaline
Harmine
Hawaiian Baby Woodrose
Hexedrone
Hydralazine
Hydrochlorothiazide
Hydrocodone
Hydrocortisone (cortisol)
Hydromorphone
Hydroquinone
Hydroxychloroquine
Hydroxyzine (hydrochloride; pamoate salt)
Hyoscyamine
Hyoscyamus niger
Iboga
Ibogaine
Ibotenic acid
Ibuprofen
Icosapent ethyl (eicosapentaenoic acid ethyl ester, EPA-EE)
Iloperidone
Imipramine
Indomethacin
Insulin aspart
Insulin degludec
Insulin detemir
Insulin glargine
Insulin lispro
Ipratropium bromide
Irbesartan
Isocarboxazid
Isoflurane
Isopropylphenidate
Isosorbide (dinitrate, mononitrate)
Ivermectin
JWH-018
JWH-073
Kava
Ketoconazole
Ketorolac (tromethamine)
Ketotifen
Khat
Kola
Kratom
L-Theanine
LSA
LSD
LSH
LSZ
Labetalol
Lacosamide
Lactated Ringer's solution
Lactulose
Lamotrigine
Lasmiditan
Latanoprost
Levetiracetam
Levocetirizine
Levodopa
Levofloxacin
Levomilnacipran
Levorphanol
Levothyroxine
Lidocaine (hydrochloride)
Linaclotide
Linagliptin
Liothyronine (T3, triiodothyronine sodium)
Liraglutide
Lisdexamfetamine (dimesylate)
Lisinopril
Lithium
Lixisenatide
Lofexidine
Loperamide
Loratadine
Lorazepam
Lormetazepam
Losartan
Lovastatin
Loxapine
Lurasidone
MDA
MDAI
MDEA
MDMA
MDPV
MET
Magnesium (oxide, citrate, sulfate, hydroxide, gluconate, chloride salts)
Mandragora officinarum
Maprotiline
Meclizine
Medroxyprogesterone acetate (MPA)
Melatonin (N-acetyl-5-methoxytryptamine)
Meloxicam
Memantine
Memantine ER / Donepezil
Meperidine
Mephedrone
Meprobamate
Mesalamine (5-aminosalicylic acid, 5-ASA)
Mescal Bean
Metaxalone
Metformin
Methadone
Methallylescaline
Methamphetamine
Methaqualone
Methcathinone
Methimazole (thiamazole)
Methiopropamine
Methocarbamol
Methohexital
Methotrexate
Methoxetamine
Methylnaphthidate
Methylone
Methylphenidate
Methylprednisolone
Metizolam
Metoclopramide
Metoprolol
Metronidazole
Mexedrone
MiPLA
MiPT
Midazolam
Milnacipran
Mimosa hostilis
Mirabegron
Mirtazapine
Mitragynine
Mixed amphetamine salts
Moclobemide
Modafinil
Molindone
Mometasone furoate
Montelukast
Morning Glory
Morphine (sulfate)
Moxifloxacin
Mupirocin
Muscimol
Myristicin
N-Ethylhexedrone
N-Ethylpentedrone
NM-2-AI
Nabilone
Nabiximols
Nabumetone
Nadolol
Nalbuphine
Nalmefene
Naloxone
Naltrexone
Naproxen (sodium; free acid)
Naratriptan
Nebivolol
Nefazodone
Niacin (nicotinic acid, vitamin B3)
Nicotine
Nifedipine
Nifoxipam
Nitrazepam
Nitrofurantoin
Nitroglycerin (glyceryl trinitrate, GTN)
Nitromethaqualone
Nitrous oxide
Noopept
Norethindrone (norethisterone outside US)
Nortriptyline (hydrochloride)
Nutmeg
Nystatin
O-Desmethyltramadol
O-PCE
Ofloxacin
Olanzapine
Olanzapine / Fluoxetine
Olmesartan (medoxomil)
Olopatadine
Omega-3-acid ethyl esters
Omeprazole
Ondansetron
Opicapone
Orphenadrine
Oseltamivir
Oxazepam
Oxcarbazepine
Oxiracetam
Oxybutynin
Oxycodone (hydrochloride)
Oxycodone / Acetaminophen
Oxycodone / Aspirin
Oxymorphone
PMA
PMMA
PRO-LAD
Paliperidone
Pantoprazole
Papaverine
Paracetamol
Paroxetine (HCl; mesylate as Pexeva)
Penicillin G (benzylpenicillin; potassium, sodium, benzathine, procaine salts)
Penicillin V (phenoxymethylpenicillin)
Pentazocine
Pentedrone
Pentobarbital
Perampanel
Perphenazine
Peyote
Phalaris arundinaceae
Phenazopyridine
Phencyclidine
Phenelzine
Phenethylamine
Phenibut
Phenobarbital
Phentermine
Phenylpiracetam
Phenytoin
Pimozide
Pioglitazone
Piracetam
Piroxicam
Polyethylene glycol 3350 (PEG 3350)
Polyethylene glycol 3350 with electrolytes
Potassium chloride
Pramipexole
Pramiracetam
Pravastatin
Prazosin
Prednisolone (and prednisolone sodium phosphate, acetate, etc.)
Prednisone
Pregabalin
Primidone
Procaine
Prochlorperazine
Progesterone (micronized)
Prolintane
Promethazine (hydrochloride)
Propofol
Propranolol
Propylhexedrine
Proscaline
Protriptyline
Pseudoephedrine (hydrochloride; sulfate)
Psilocin
Psilocybin
Psilocybin mushrooms
Psychotria viridis
Pyrazolam
Quazepam
Quetiapine
RTI-111
Ramelteon
Ramipril
Rasagiline
Reboxetine
Remifentanil
Riboflavin (vitamin B2)
Rimegepant
Risperidone
Rivaroxaban
Rivastigmine
Rizatriptan (benzoate)
Ropinirole
Ropivacaine
Rosuvastatin
Rotigotine
Rufinamide
STS-135
Safinamide
Salvia divinorum
Salvinorin A
San Pedro cactus
Scopolamine
Secobarbital
Selegiline
Semaglutide
Semax
Sertraline
Sevoflurane
Sildenafil
Simvastatin
Sitagliptin
Sodium Oxybate
Sodium bicarbonate
Sodium chloride
Sodium fluoride
Solifenacin
Sotalol
Spironolactone
Stiripentol
Sucralfate
Sufentanil
Sumatriptan (succinate)
Sumatriptan / Naproxen
Syrian rue
THC
THCP
THJ-018
THJ-2201
TMA-2
Tadalafil
Tamsulosin
Tapentadol
Tasimelteon
Tea
Telmisartan
Temazepam
Terazosin
Terbinafine
Testosterone
Tetrahydrocannabivarin
Tetrahydroharmine
Theacrine
Thebaine
Theophylline
Thiopental
Thioridazine
Thiothixene
Thyroid (desiccated)
Tiagabine
Tianeptine
Ticagrelor
Timolol (maleate)
Tiotropium
Tirzepatide
Tizanidine
Tobramycin
Tolcapone
Topiramate
Torsemide
Tramadol
Tramadol / Acetaminophen
Tranylcypromine
Trazodone
Tretinoin (all-trans retinoic acid, ATRA)
Triamcinolone (acetonide and other esters)
Triazolam
Trifluoperazine
Trihexyphenidyl
Trimipramine
U-47700
Ubrogepant
Valacyclovir
Valproate (valproic acid, divalproex sodium, sodium valproate)
Valproic acid
Valsartan
Vardenafil
Varenicline
Venlafaxine
Verapamil
Vigabatrin
Vitamin E (α-tocopherol; mixed natural and synthetic forms)
Warfarin
Xenon
Yerba mate
Yopo
Zaleplon
Ziprasidone
Zolmitriptan
Zolpidem (tartrate)
Zonisamide
Zopiclone
aMT
alpha-PHP
alpha-PVP
ketamine
mCPP
mescaline
opium
Search
brand:
''Sophora secundiflora''. Texas mountain laurel, frijolillo (1)
classes:
Phantastica (1)
·
Plant Medicine (1)
mechanism:
Active alkaloid is cytisine, a nicotinic acetylcholine receptor agonist. NOT a classical 5-HT2A psychedelic. (1)
uses:
(Click arrow to add another value)
None
·
'"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"', '"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"', '"`UNIQ--vote-00000023-QINU`"', '"`UNIQ--vote-00000024-QINU`"', '"`UNIQ--vote-00000025-QINU`"'
·
'"`UNIQ--vote-00000008-QINU`"', '"`UNIQ--vote-00000009-QINU`"'
·
'"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"'
·
'"`UNIQ--vote-00000017-QINU`"', '"`UNIQ--vote-00000018-QINU`"', '"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"'
·
'"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"', '"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"'
·
'"`UNIQ--vote-00000006-QINU`"'
·
'"`UNIQ--vote-00000017-QINU`"', '"`UNIQ--vote-00000018-QINU`"', '"`UNIQ--vote-00000019-QINU`"'
·
'"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"', '"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"'
·
'"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"', '"`UNIQ--vote-00000023-QINU`"', '"`UNIQ--vote-00000024-QINU`"', '"`UNIQ--vote-00000025-QINU`"', '"`UNIQ--vote-00000026-QINU`"', '"`UNIQ--vote-00000027-QINU`"', '"`UNIQ--vote-00000028-QINU`"'
·
'"`UNIQ--vote-00000013-QINU`"', '"`UNIQ--vote-00000014-QINU`"'
·
'"`UNIQ--vote-00000015-QINU`"', '"`UNIQ--vote-00000016-QINU`"'
·
Preventive treatment of migraine in adults (episodic and chronic)
·
'"`UNIQ--vote-00000015-QINU`"', '"`UNIQ--vote-00000016-QINU`"', '"`UNIQ--vote-00000017-QINU`"'
·
(investigational) '"`UNIQ--vote-000000EF-QINU`"', '"`UNIQ--vote-000000F0-QINU`"', '"`UNIQ--vote-000000F1-QINU`"', '"`UNIQ--vote-000000F2-QINU`"', '"`UNIQ--vote-000000F3-QINU`"'
·
Acute treatment of migraine with or without aura in adults
·
ADHD in children (6+), adolescents, and adults (FDA-approved 2021 for pediatric, 2022 for adult)
·
ADHD, narcolepsy
·
Alzheimer disease (FDA accelerated approval June 2021; '''withdrawn from market January 2024''' by manufacturer Biogen). At time of approval indicated for MCI or mild dementia stage of AD.
·
Alzheimer disease (MCI or mild dementia stage), FDA-approved July 2024
Other values:
Alzheimer disease (MCI or mild dementia stage); FDA accelerated approval Jan 2023 → traditional approval July 2023
Chronic migraine (≥15 headache days/month), cervical dystonia, blepharospasm, hyperhidrosis, overactive bladder, urinary incontinence, strabismus, spasticity, cosmetic problems
Depression, anxiety, neuropathic pain, fibromyalgia, chronic musculoskeletal pain
Excessive daytime sleepiness in adults with narcolepsy or obstructive sleep apnea (OSA)
Excessive daytime sleepiness or cataplexy in adults with narcolepsy (FDA-approved August 2019)
Hallucinations and delusions associated with Parkinson's disease psychosis (PDP). Investigational for psychosis in other dementias and as augmentation for depression.
Insomnia (sleep onset and/or maintenance) in adults (FDA-approved August 2014). Also studied for insomnia in mild-moderate Alzheimer disease.
Insomnia (sleep onset and/or maintenance) in adults (FDA-approved Dec 2019)
Insomnia (sleep onset and/or sleep maintenance) in adults (FDA-approved Jan 2022)
Investigational for major depressive disorder; trials underway (phase 3 mixed results)
Major depressive disorder in adults (FDA-approved 2011)
Major depressive disorder in adults (FDA-approved 2013). Notable for evidence of cognitive benefit (processing speed) that distinguishes it from other antidepressants.
Major depressive disorder in adults (FDA-approved August 2022)
Mild to moderate pain; cough suppression (low-dose).
No approved medical problem. Encountered as a designer/research benzodiazepine and, increasingly, as an adulterant in illicit opioid supplies.
Pain, cough, disquiet
Postpartum depression (PPD) in adults
Postpartum depression (PPD) in adults (FDA-approved 2023)
Preventive treatment of migraine in adults
Preventive treatment of migraine in adults; episodic cluster headache
Schizophrenia (FDA-approved 2015). Acute manic or mixed episodes of bipolar I disorder. Bipolar I depression (FDA-approved 2019). Adjunctive treatment of major depressive disorder (FDA-approved Dec 2022).
Schizophrenia (FDA-approved 2015). Adjunctive treatment of major depressive disorder (2015). '''Agitation associated with dementia due to Alzheimer disease''' (FDA-approved May 2023, first agent specifically approved for this problem). Investigational for PTSD (combined with sertraline).
Schizophrenia (FDA-approved Dec 2019). Bipolar depression as monotherapy or adjunct to lithium/valproate (FDA-approved Dec 2021).
Schizophrenia, acute psychosis, agitation, delirium, Tourette syndrome, severe nausea
Treatment-resistant depression (TRD) in adults, as adjunct to oral antidepressant (FDA-approved March 2019). Depressive symptoms in adults with MDD with acute suicidal ideation or behavior (FDA-approved Aug 2020).
[[Type 2 diabetes mellitus]] (adjunct, second-line)
[[Type 2 diabetes mellitus]] (incl. pediatric ≥10 y) · [[Obesity]] (incl. pediatric ≥12 y) · [[Cardiovascular risk reduction]] in T2DM
[[Type 2 diabetes mellitus]] · [[Cardiovascular risk reduction]] in T2DM
[[Type 2 diabetes mellitus]] · [[Obesity]] · [[Cardiovascular risk reduction]] in obesity without diabetes · [[MASH]] with stage 2–3 fibrosis · [[Chronic kidney disease]] in T2DM
[[Type 2 diabetes mellitus]] · [[Obesity]] · [[Obstructive sleep apnea]] in obesity
'"`UNIQ--vote-0000000C-QINU`"', '"`UNIQ--vote-0000000D-QINU`"', '"`UNIQ--vote-0000000E-QINU`"', '"`UNIQ--vote-0000000F-QINU`"'
'"`UNIQ--vote-00000011-QINU`"'
'"`UNIQ--vote-00000013-QINU`"'
'"`UNIQ--vote-00000017-QINU`"'
'"`UNIQ--vote-00000018-QINU`"', '"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"'
'"`UNIQ--vote-00000018-QINU`"', '"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"', '"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"'
'"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"', '"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"'
'"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"'
'"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"'
'"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"'
'"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"', '"`UNIQ--vote-00000021-QINU`"'
'"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"', '"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"', '"`UNIQ--vote-00000023-QINU`"', '"`UNIQ--vote-00000024-QINU`"', '"`UNIQ--vote-00000025-QINU`"', '"`UNIQ--vote-00000026-QINU`"'
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'"`UNIQ--vote-00000BBC-QINU`"', '"`UNIQ--vote-00000BBD-QINU`"'
'"`UNIQ--vote-00000BE3-QINU`"', '"`UNIQ--vote-00000BE4-QINU`"', '"`UNIQ--vote-00000BE5-QINU`"', '"`UNIQ--vote-00000BE6-QINU`"', '"`UNIQ--vote-00000BE7-QINU`"', '"`UNIQ--vote-00000BE8-QINU`"', '"`UNIQ--vote-00000BE9-QINU`"', '"`UNIQ--vote-00000BEA-QINU`"'
'"`UNIQ--vote-00000C0A-QINU`"', '"`UNIQ--vote-00000C0B-QINU`"', '"`UNIQ--vote-00000C0C-QINU`"', '"`UNIQ--vote-00000C0D-QINU`"', '"`UNIQ--vote-00000C0E-QINU`"'
'"`UNIQ--vote-00000C2E-QINU`"', '"`UNIQ--vote-00000C2F-QINU`"', '"`UNIQ--vote-00000C30-QINU`"', '"`UNIQ--vote-00000C31-QINU`"'
'"`UNIQ--vote-00000C4C-QINU`"', '"`UNIQ--vote-00000C4D-QINU`"'
'"`UNIQ--vote-00000C6D-QINU`"', '"`UNIQ--vote-00000C6E-QINU`"', '"`UNIQ--vote-00000C6F-QINU`"', '"`UNIQ--vote-00000C70-QINU`"', '"`UNIQ--vote-00000C71-QINU`"'
'"`UNIQ--vote-00000C8F-QINU`"', '"`UNIQ--vote-00000C90-QINU`"', '"`UNIQ--vote-00000C91-QINU`"'
'"`UNIQ--vote-00000CB0-QINU`"', '"`UNIQ--vote-00000CB1-QINU`"', '"`UNIQ--vote-00000CB2-QINU`"'
'"`UNIQ--vote-00000CCA-QINU`"', '"`UNIQ--vote-00000CCB-QINU`"'
'"`UNIQ--vote-00000CEF-QINU`"', '"`UNIQ--vote-00000CF0-QINU`"', '"`UNIQ--vote-00000CF1-QINU`"', '"`UNIQ--vote-00000CF2-QINU`"', '"`UNIQ--vote-00000CF3-QINU`"', '"`UNIQ--vote-00000CF4-QINU`"'
'"`UNIQ--vote-00000D13-QINU`"', '"`UNIQ--vote-00000D14-QINU`"', '"`UNIQ--vote-00000D15-QINU`"', '"`UNIQ--vote-00000D16-QINU`"'
'"`UNIQ--vote-00000D38-QINU`"', '"`UNIQ--vote-00000D39-QINU`"', '"`UNIQ--vote-00000D3A-QINU`"', '"`UNIQ--vote-00000D3B-QINU`"', '"`UNIQ--vote-00000D3C-QINU`"', '"`UNIQ--vote-00000D3D-QINU`"'
'"`UNIQ--vote-00000D57-QINU`"', '"`UNIQ--vote-00000D58-QINU`"'
'"`UNIQ--vote-00000D7C-QINU`"', '"`UNIQ--vote-00000D7D-QINU`"', '"`UNIQ--vote-00000D7E-QINU`"', '"`UNIQ--vote-00000D7F-QINU`"', '"`UNIQ--vote-00000D80-QINU`"', '"`UNIQ--vote-00000D81-QINU`"'
'"`UNIQ--vote-00000D9E-QINU`"', '"`UNIQ--vote-00000D9F-QINU`"', '"`UNIQ--vote-00000DA0-QINU`"'
'"`UNIQ--vote-00000DBE-QINU`"', '"`UNIQ--vote-00000DBF-QINU`"', '"`UNIQ--vote-00000DC0-QINU`"', '"`UNIQ--vote-00000DC1-QINU`"'
'"`UNIQ--vote-00000DDF-QINU`"', '"`UNIQ--vote-00000DE0-QINU`"', '"`UNIQ--vote-00000DE1-QINU`"', '"`UNIQ--vote-00000DE2-QINU`"'
'"`UNIQ--vote-00000DFC-QINU`"', '"`UNIQ--vote-00000DFD-QINU`"'
'"`UNIQ--vote-00000E23-QINU`"', '"`UNIQ--vote-00000E24-QINU`"', '"`UNIQ--vote-00000E25-QINU`"', '"`UNIQ--vote-00000E26-QINU`"', '"`UNIQ--vote-00000E27-QINU`"', '"`UNIQ--vote-00000E28-QINU`"', '"`UNIQ--vote-00000E29-QINU`"', '"`UNIQ--vote-00000E2A-QINU`"'
'"`UNIQ--vote-00000E4C-QINU`"', '"`UNIQ--vote-00000E4D-QINU`"', '"`UNIQ--vote-00000E4E-QINU`"', '"`UNIQ--vote-00000E4F-QINU`"', '"`UNIQ--vote-00000E50-QINU`"', '"`UNIQ--vote-00000E51-QINU`"'
'"`UNIQ--vote-00000E71-QINU`"', '"`UNIQ--vote-00000E72-QINU`"', '"`UNIQ--vote-00000E73-QINU`"', '"`UNIQ--vote-00000E74-QINU`"', '"`UNIQ--vote-00000E75-QINU`"'
'"`UNIQ--vote-00000E91-QINU`"', '"`UNIQ--vote-00000E92-QINU`"', '"`UNIQ--vote-00000E93-QINU`"'
'"`UNIQ--vote-00000EAF-QINU`"', '"`UNIQ--vote-00000EB0-QINU`"', '"`UNIQ--vote-00000EB1-QINU`"'
'"`UNIQ--vote-00000ECF-QINU`"', '"`UNIQ--vote-00000ED0-QINU`"', '"`UNIQ--vote-00000ED1-QINU`"', '"`UNIQ--vote-00000ED2-QINU`"'
'"`UNIQ--vote-00000EF4-QINU`"', '"`UNIQ--vote-00000EF5-QINU`"', '"`UNIQ--vote-00000EF6-QINU`"', '"`UNIQ--vote-00000EF7-QINU`"', '"`UNIQ--vote-00000EF8-QINU`"'
'"`UNIQ--vote-00000F1B-QINU`"', '"`UNIQ--vote-00000F1C-QINU`"', '"`UNIQ--vote-00000F1D-QINU`"', '"`UNIQ--vote-00000F1E-QINU`"', '"`UNIQ--vote-00000F1F-QINU`"'
'"`UNIQ--vote-00000F40-QINU`"', '"`UNIQ--vote-00000F41-QINU`"', '"`UNIQ--vote-00000F42-QINU`"', '"`UNIQ--vote-00000F43-QINU`"', '"`UNIQ--vote-00000F44-QINU`"'
'"`UNIQ--vote-00000F5C-QINU`"', '"`UNIQ--vote-00000F5D-QINU`"'
'"`UNIQ--vote-00000F78-QINU`"', '"`UNIQ--vote-00000F79-QINU`"', '"`UNIQ--vote-00000F7A-QINU`"'
'"`UNIQ--vote-00000F98-QINU`"', '"`UNIQ--vote-00000F99-QINU`"', '"`UNIQ--vote-00000F9A-QINU`"', '"`UNIQ--vote-00000F9B-QINU`"'
'"`UNIQ--vote-00000FB3-QINU`"', '''adjunctive only''' (does not treat the underlying infection)
'"`UNIQ--vote-00000FCF-QINU`"', '"`UNIQ--vote-00000FD0-QINU`"', '"`UNIQ--vote-00000FD1-QINU`"'
'"`UNIQ--vote-00000FF3-QINU`"', '"`UNIQ--vote-00000FF4-QINU`"', '"`UNIQ--vote-00000FF5-QINU`"', '"`UNIQ--vote-00000FF6-QINU`"', '"`UNIQ--vote-00000FF7-QINU`"', '"`UNIQ--vote-00000FF8-QINU`"'
'"`UNIQ--vote-00001016-QINU`"', '"`UNIQ--vote-00001017-QINU`"', '"`UNIQ--vote-00001018-QINU`"', '"`UNIQ--vote-00001019-QINU`"'
'"`UNIQ--vote-00001035-QINU`"', '"`UNIQ--vote-00001036-QINU`"', '"`UNIQ--vote-00001037-QINU`"'
'"`UNIQ--vote-0000104E-QINU`"', '"`UNIQ--vote-0000104F-QINU`"'
'"`UNIQ--vote-00001069-QINU`"', '"`UNIQ--vote-0000106A-QINU`"'
'"`UNIQ--vote-0000108C-QINU`"', '"`UNIQ--vote-0000108D-QINU`"', '"`UNIQ--vote-0000108E-QINU`"', '"`UNIQ--vote-0000108F-QINU`"', '"`UNIQ--vote-00001090-QINU`"', '"`UNIQ--vote-00001091-QINU`"'
'"`UNIQ--vote-000010AF-QINU`"', '"`UNIQ--vote-000010B0-QINU`"', '"`UNIQ--vote-000010B1-QINU`"', '"`UNIQ--vote-000010B2-QINU`"'
'"`UNIQ--vote-000010CE-QINU`"', '"`UNIQ--vote-000010CF-QINU`"', '"`UNIQ--vote-000010D0-QINU`"'
'"`UNIQ--vote-0000111D-QINU`"', '"`UNIQ--vote-0000111E-QINU`"'
'"`UNIQ--vote-0000113C-QINU`"', '"`UNIQ--vote-0000113D-QINU`"', '"`UNIQ--vote-0000113E-QINU`"'
'"`UNIQ--vote-0000115F-QINU`"', '"`UNIQ--vote-00001160-QINU`"', '"`UNIQ--vote-00001161-QINU`"', '"`UNIQ--vote-00001162-QINU`"', '"`UNIQ--vote-00001163-QINU`"'
'"`UNIQ--vote-0000117B-QINU`"'
'"`UNIQ--vote-00001199-QINU`"', '"`UNIQ--vote-0000119A-QINU`"', '"`UNIQ--vote-0000119B-QINU`"'
'"`UNIQ--vote-000011BA-QINU`"', '"`UNIQ--vote-000011BB-QINU`"', '"`UNIQ--vote-000011BC-QINU`"', '"`UNIQ--vote-000011BD-QINU`"'
'"`UNIQ--vote-000011D7-QINU`"', '"`UNIQ--vote-000011D8-QINU`"'
'"`UNIQ--vote-000011F6-QINU`"', '"`UNIQ--vote-000011F7-QINU`"', '"`UNIQ--vote-000011F8-QINU`"'
'"`UNIQ--vote-00001215-QINU`"', '"`UNIQ--vote-00001216-QINU`"', '"`UNIQ--vote-00001217-QINU`"'
'"`UNIQ--vote-00001235-QINU`"', '"`UNIQ--vote-00001236-QINU`"', '"`UNIQ--vote-00001237-QINU`"', '"`UNIQ--vote-00001238-QINU`"'
'"`UNIQ--vote-0000124D-QINU`"', '"`UNIQ--vote-0000124E-QINU`"', '"`UNIQ--vote-0000124F-QINU`"'
'"`UNIQ--vote-0000126B-QINU`"', '"`UNIQ--vote-0000126C-QINU`"', '"`UNIQ--vote-0000126D-QINU`"'
'"`UNIQ--vote-00001286-QINU`"'
'"`UNIQ--vote-0000129E-QINU`"'
'"`UNIQ--vote-000012B7-QINU`"', '"`UNIQ--vote-000012B8-QINU`"', '"`UNIQ--vote-000012B9-QINU`"', '"`UNIQ--vote-000012BA-QINU`"', '"`UNIQ--vote-000012BB-QINU`"'
'"`UNIQ--vote-000012CE-QINU`"', '"`UNIQ--vote-000012CF-QINU`"', '"`UNIQ--vote-000012D0-QINU`"'
'"`UNIQ--vote-000012E5-QINU`"', '"`UNIQ--vote-000012E6-QINU`"', '"`UNIQ--vote-000012E7-QINU`"', '"`UNIQ--vote-000012E8-QINU`"'
'"`UNIQ--vote-00001303-QINU`"', '"`UNIQ--vote-00001304-QINU`"', '"`UNIQ--vote-00001305-QINU`"', '"`UNIQ--vote-00001306-QINU`"', '"`UNIQ--vote-00001307-QINU`"', '"`UNIQ--vote-00001308-QINU`"', '"`UNIQ--vote-00001309-QINU`"'
'"`UNIQ--vote-0000131A-QINU`"', '"`UNIQ--vote-0000131B-QINU`"'
'"`UNIQ--vote-0000132E-QINU`"', '"`UNIQ--vote-0000132F-QINU`"', '"`UNIQ--vote-00001330-QINU`"'
'"`UNIQ--vote-00001341-QINU`"', '"`UNIQ--vote-00001342-QINU`"'
'"`UNIQ--vote-00001358-QINU`"', '"`UNIQ--vote-00001359-QINU`"'
'"`UNIQ--vote-00001372-QINU`"', '"`UNIQ--vote-00001373-QINU`"'
'"`UNIQ--vote-00001393-QINU`"', '"`UNIQ--vote-00001394-QINU`"', '"`UNIQ--vote-00001395-QINU`"', '"`UNIQ--vote-00001396-QINU`"', '"`UNIQ--vote-00001397-QINU`"'
'"`UNIQ--vote-000013B3-QINU`"', '"`UNIQ--vote-000013B4-QINU`"', '"`UNIQ--vote-000013B5-QINU`"'
'"`UNIQ--vote-000013CF-QINU`"', '"`UNIQ--vote-000013D0-QINU`"'
'"`UNIQ--vote-000013F0-QINU`"', '"`UNIQ--vote-000013F1-QINU`"', '"`UNIQ--vote-000013F2-QINU`"', '"`UNIQ--vote-000013F3-QINU`"', '"`UNIQ--vote-000013F4-QINU`"'
'"`UNIQ--vote-00001414-QINU`"', '"`UNIQ--vote-00001415-QINU`"', '"`UNIQ--vote-00001416-QINU`"', '"`UNIQ--vote-00001417-QINU`"', '"`UNIQ--vote-00001418-QINU`"'
'"`UNIQ--vote-0000143C-QINU`"', '"`UNIQ--vote-0000143D-QINU`"', '"`UNIQ--vote-0000143E-QINU`"', '"`UNIQ--vote-0000143F-QINU`"', '"`UNIQ--vote-00001440-QINU`"', '"`UNIQ--vote-00001441-QINU`"'
'"`UNIQ--vote-0000145E-QINU`"', '"`UNIQ--vote-0000145F-QINU`"', '"`UNIQ--vote-00001460-QINU`"'
'"`UNIQ--vote-0000147C-QINU`"', '"`UNIQ--vote-0000147D-QINU`"', '"`UNIQ--vote-0000147E-QINU`"'
'"`UNIQ--vote-0000149A-QINU`"', '"`UNIQ--vote-0000149B-QINU`"', '"`UNIQ--vote-0000149C-QINU`"'
'"`UNIQ--vote-000014BE-QINU`"', '"`UNIQ--vote-000014BF-QINU`"', '"`UNIQ--vote-000014C0-QINU`"', '"`UNIQ--vote-000014C1-QINU`"', '"`UNIQ--vote-000014C2-QINU`"'
'"`UNIQ--vote-000014DF-QINU`"', '"`UNIQ--vote-000014E0-QINU`"', '"`UNIQ--vote-000014E1-QINU`"'
'"`UNIQ--vote-000014F9-QINU`"'
'"`UNIQ--vote-00001515-QINU`"', '"`UNIQ--vote-00001516-QINU`"'
'"`UNIQ--vote-0000152F-QINU`"'
'"`UNIQ--vote-0000154B-QINU`"', '"`UNIQ--vote-0000154C-QINU`"'
'"`UNIQ--vote-00001567-QINU`"'
'"`UNIQ--vote-00001582-QINU`"'
'"`UNIQ--vote-0000159D-QINU`"', '"`UNIQ--vote-0000159E-QINU`"'
'"`UNIQ--vote-000015B6-QINU`"'
'"`UNIQ--vote-000015D0-QINU`"'
Search
starting dose:
None
(1)
preparations:
Bright red seeds, traditionally ingested or smoked. Highly toxic, narrow margin between active and lethal (1)
fda max:
None
(1)
routes:
Oral (1)
onset:
(Click arrow to add another value)
None
·
Hours
·
30-60 minutes
·
1-2 hours
·
~30 min
·
LDL lowering at 2 weeks, max by 4 weeks
·
~1 hour
·
15-30 minutes
·
15–30 min
·
1–2 h
·
30–60 min
·
Antidepressant effect emerges over 1-2 weeks
·
BP and symptomatic LUTS improvement within 1-2 weeks
·
BP effect within 1-2 weeks
·
Clinical improvement within 24-72 hours
·
Days
·
Motor improvement over days at therapeutic dose
·
Over weeks
·
Postprandial glucose effect within days; HbA1c by 12 weeks
·
Sleep effect from first dose; antidepressant effect over 1-4 weeks
Other values:
'''Anxiolytic effect emerges over 2-4 weeks'''; buspirone does NOT work for acute anxiety, which is the central teaching point and the most common cause of treatment failure
1 hour PO; minutes IV
1-2 hours (oral)
1-2 hours (slower than immediate-release amphetamine because activation requires enzymatic cleavage in red blood cells)
1-2 hours PO
1-2 hours for migraine relief
1-2 weeks for antidepressant effect; smoking-cessation effect builds over the first 1-2 weeks
1-2 weeks for neuropathic pain and anxiolytic effect; anticonvulsant effect at therapeutic plasma level
1-3 days
1-3 hours (slower onset than cetirizine; symptom relief somewhat less)
10 minutes (SC); 15-30 minutes (nasal); 30-60 minutes (oral)
10-30 minutes
10-30 minutes (IR)
15 minutes
15-20 minutes
15-30 minutes (oral)
15-30 minutes (oral); 1-2 minutes (IV)
15-60 minutes (oral); 1-5 minutes (IV); 4-10 minutes (rectal or intranasal)
15–30 min (fasting)
1–2 h (PO), immediate (IV)
1–2 h (PO); immediate (IV)
1–2 weeks for muscle effects; preventive migraine benefit accrues over 12-week cycles
2-3 hours per dose; full acid suppression after 3-5 days
20 minutes (oral); 5 minutes (IV)
20-45 min subjective onset; psilocin formation from psilocybin requires intestinal and hepatic alkaline phosphatase
20-60 minutes
20–60 min (oral)
30 min
30 minutes
30 minutes (IM); 30-60 minutes (oral)
30 minutes PO; minutes IV
30 minutes for migraine relief
30-60 min (IR oral); 2-3 days to steady state (transdermal patch)
30-60 min (immediate-release); 1-2 h (extended-release)
30-60 min (sedation); days to weeks (neuroleptic effect)
30-60 minutes (IR)
30-60 minutes (PO)
30-60 minutes (immediate-release oral)
30-60 minutes (oral)
30-60 minutes (oral); 5 minutes (IV); 15-30 minutes (IM)
30-60 minutes (oral); rapid relief in acute gout
30-60 minutes (oral); slower for topical
30–60 min (PO)
30–60 min (SL)
30–60 minutes
30–90 min
4-6 weeks for full antidepressant effect (claimed earlier onset for some patients due to 5HT1A partial agonism)
45-75 min (oral)
5-10 minutes (IV); 30 minutes (oral IR); slower for ER and rectal
<1 minute (IV); 1-2 minutes (infiltration); 30+ minutes (patch on adult skin, faster on thinner pediatric skin)
ADHD effect emerges over 1-2 weeks (slower than psychostimulants); full effect 4-6 weeks
ADHD symptom improvement reported within 1-2 weeks (faster than atomoxetine which takes 4-6 weeks)
AF conversion within hours of single PO dose
Acid suppression within hours; full effect after 3-5 days of dosing
Acute: minutes (IV); chronic: bone effect over months
Amyloid PET clearance within months; cognitive benefit over 18 months
Analgesia within 30 minutes; full anti-inflammatory effect over days
Analgesia within hours; anti-inflammatory effect over days
Analgesic effect within hours; full anti-inflammatory effect over 1-2 weeks
Anti-inflammatory effect within 24 hours of gout flare onset; loses effectiveness if delayed
Anticoagulant effect at 24-72 hours; full INR effect 5-7 days
Anticonvulsant effect emerges with slow titration over weeks; tremor effect over weeks
Anticonvulsant effect within days at therapeutic level; migraine prophylaxis effect emerges over 2-3 months
Anticonvulsant effect within days at therapeutic plasma level
Anticonvulsant effect within days at therapeutic plasma level; rapid titration possible
Anticonvulsant effect within days; mood-stabilizing effect 1-3 weeks
Anticonvulsant effect within days; trigeminal neuralgia relief 24-72 hours; mood-stabilizing effect over weeks
Antidepressant effect emerges over 1-2 weeks; full clinical effect 4-6 weeks
Antidepressant effect over 1-2 weeks; anxiolytic effect over 4-6 weeks
Antidepressant effect over 1-2 weeks; full clinical effect 4-6 weeks
Antidepressant effect within hours of infusion start; sustained at 30 days
Antiepileptic effect within days at therapeutic level; mood-stabilizing effect emerges over weeks
Antihypertensive effect within 1 week; heart-failure mortality benefit accrues over months of titration
Antimanic effects begin within 5-7 days of reaching therapeutic serum levels, with full response often requiring 2-3 weeks. For acute mania, a neuroleptic is typically added for rapid sedation while lithium takes effect.'"`UNIQ--ref-00000053-QINU`"'
Antiplatelet effect within 2 hours of a loading dose; steady-state at 5-7 days of maintenance dosing
Antiplatelet effect within 30 minutes of loading dose (faster than clopidogrel)
Antiplatelet effect within 30-60 minutes; analgesic effect 30-60 minutes
Antipsychotic effect over weeks
Anxiolysis classically 3-4 weeks, continuing improvement to 8-12 weeks
Appetite suppression within hours; weight loss over weeks-months
BP effect 1 hour; max at 4-6 hours
BP effect 1-2 hours; max at 6 hours
BP effect 1-2 weeks; antihypertensive peak 3-6 weeks
BP effect 1-2 weeks; max at 2-3 weeks
BP effect 2 hours; max at 4-6 weeks
BP effect within 24 hours; full effect at 1-2 weeks (long half-life)
BP effect within hours (oral); 5-10 minutes (IV)
BP effect within hours (oral); IOP reduction within 30 minutes, full effect 1-2 weeks (ophthalmic)
BP effect within hours; full effect over 1-2 weeks
BP lowering within 1 hour; max at 6 hours
BP lowering within 1 hour; max effect at 6 hours
BPH symptom improvement at 3-6 months; prostate volume reduction over 6-12 months; hair regrowth at 6-12 months
Benefit over weeks of dosing
Biochemical improvement within 2-4 weeks; full euthyroid state 6-12 weeks
Bone marker reduction within weeks; BMD improvement at 1-3 years; fracture-risk reduction documented at 3-5 years
Bowel movement within 1 week; abdominal pain improvement over weeks
Bronchodilation 15-30 minutes
Bronchodilation 30 minutes; steady-state at 1-2 weeks
Bronchodilation within 1-2 hours; full controller effect 1-2 weeks
Caries reduction over months to years of consistent use
Clinical and mycologic cure follows the full course; nail clearance over months of regrowth
Cognitive effect emerges gradually over weeks to months; ceiling effect at the therapeutic dose
Cognitive effect emerges gradually over weeks to months; symptomatic effect only
Component effects accumulate over weeks
Constipation: 1-3 days; bowel prep: 1-3 hours after starting
Constipation: 24-48 hours; HE: ammonia reduction within hours of stool production
Contraception within 48 hours of starting (POP); endometrial effects days
Contraceptive within 24 hours if given in first 5 days of cycle; otherwise backup for 7 days
Day 3 of dosing in trials; sustained through day 45
Days for calcium effect; weeks for PTH suppression
Days for dermatophyte clearance; nail clearance over months
Days for immunosuppressive effect
Days for symptom improvement in scurvy
Days to weeks for tissue saturation
Days to weeks to raise 25(OH)D; clinical effect on bone over months
Diuresis at 2 hours; antihypertensive effect within days, max at 3-4 weeks
Diuresis at 2-3 hours; BP effect over weeks
Effect demonstrated within 24 hours in some patients
Effects accumulate over weeks; assess at 8 weeks
Estrogen suppression within days; clinical effect over months
First bowel movement within 1-2 hours
Glucose lowering within days; HbA1c effect at 8-12 weeks
Glycemic effect within days; full weight effect over months'"`UNIQ--ref-00000301-QINU`"'
Glycemic effect within days; near-maximal HbA1c effect by 4 weeks at any given dose'"`UNIQ--ref-00000057-QINU`"'
Glycemic effect within days; weight effect over weeks to months'"`UNIQ--ref-00000188-QINU`"'
Glycemic effect within days;<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> full weight effect over months'"`UNIQ--ref-00000250-QINU`"'
Glycemic effect within hours (Byetta); weeks (Bydureon, extended-release microsphere)'"`UNIQ--ref-000000EA-QINU`"'
Glycosuria within hours; HbA1c effect at 12 weeks; CV/renal benefits over months
Glycosuria within hours; HbA1c effect at 12 weeks; cardiovascular and renal benefits over months
Gradual; full clinical effect over 2-4 weeks of titration
HbA1c effect at 12-16 weeks (slower than other classes)
Headache relief at 30-60 minutes
Hematologic response within days
Hours (PO); IV faster but rate-limited
Hours (faster than T4); peak biologic activity 24-48 hours
Hours (systemic); minutes (ophthalmic)
Hours (transdermal); days (IM esters)
Hours to days
Hours to days for inflammation; substantial improvement within 1 week
IM: 5-10 minutes; IV: seconds; nebulized: 5-10 minutes
IOP lowering at 1 hour; max at 2-3 hours
IOP lowering at 2 hours; max at 4 hours
IOP lowering at 3-4 hours; maximum at 8-12 hours
IOP lowering at 4 hours, maximum at 8-12 hours; eyelash effect after 2 months
IR 20 minutes; ER ~6 hours
IR: 30–60 min; XR: 1–2 h to peak effect
IV pulse: hours; PO: hours; intra-articular: days
IV/IM 1-3 minutes; PO 30-60 minutes
IV: 1-3 minutes (SVT termination); PO IR: 30-60 minutes; ER: hours
IV: 3-7 minutes (rate control); PO IR: 30-60 minutes; ER: hours
IV: 5 minutes; PO: 30-60 minutes
IV: 5-20 minutes; PO: 30-60 minutes
IV: minutes; IM benzathine: depot levels last weeks
IV: minutes; oral: weeks to load
Immediate (IV)
Immediate (IV); within minutes (oral antacid)
Immediate intravascular expansion
Inhaled: 5-15 minutes; PO: 30 minutes
Inhaled: bronchial effect 1-2 weeks; nasal: symptom relief 12-24 hours; topical: hours
Inhaled: bronchial effect 1-2 weeks; oral GI effect 1-2 weeks
Intranasal: symptom relief 12-24 hours; inhaled: bronchial effect 1-2 weeks
LDL lowering at 1 week, max by 4 weeks
LDL lowering at 2 weeks, max by 4 weeks; cardiovascular benefit months to years
LDL lowering within 2 weeks
LDL reduction ~50-60% from baseline at 1-2 weeks
Lipid changes 4-8 weeks
Migraine effect after 1-3 months of daily use
Minutes
Modest appetite suppression within weeks; weight loss over months
Mood improvement at 1-3 weeks; full effect 4-6 weeks
Mood: 2–4 weeks. Pain: often within 1–2 weeks.
Mucosal protection within hours; ulcer healing over 2-4 weeks
Natriuresis at 2-3 days; endocrine effects (gynecomastia, antiandrogen action) over weeks
Neuroleptic effect emerges over days to weeks
Neuroleptic effect emerges over days to weeks; activation symptoms (akathisia, insomnia) often within days
Neuropathic pain and fibromyalgia effect emerges over 1-2 weeks
OCD effect over 1-2 weeks initial, with full effect typically 6-12 weeks; among the slowest SSRIs for OCD response
Onset of preventive effect over weeks; some patients respond after first dose
Oral analgesic effect 30-60 minutes; opioid-withdrawal suppression 30 minutes (oral); IV ~10 minutes
Oral peak plasma 1 hour; therapeutic opioid blockade within hours of first dose. IM Vivitrol: peak plasma 2-3 days; therapeutic blockade through the dosing interval.
Oral peak plasma 2.5 hours. Clinical antipsychotic response typically emerges over weeks with continued titration; full response assessment requires 3-6 months at adequate therapeutic levels.
Oral: hours; IV: minutes
PBA episode reduction within 1-2 weeks
PET Aβ reduction over months
PO 1 hour; IV 10 minutes
PO 1–2 h; IM 30–60 min; IV 5–20 min
PO 30-60 minutes; IV minutes
PO 6-12 hours; PR 15-60 minutes
PO: 30-60 minutes; IV: minutes
Pain and migraine prophylaxis effect 1-4 weeks; antidepressant effect 4-6 weeks
Pain relief reported within 15 min in trials
Peak anticoagulant effect 2-4 hours
Peak anticoagulant effect 3-4 hours
Peak plasma at 1-2 hours; clinical effect within 24-72 hours
Peak plasma concentration in 2-4 hours after oral administration. Clinically perceptible wakefulness-promoting effects typically begin within 1-2 hours of dosing.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Prostate volume reduction over 6-12 months
Rapid (within 1 week in trials)
Reticulocyte response at 3-5 days; neurologic recovery weeks to months (and may be incomplete if longstanding)
Reticulocyte response at 7-10 days; hemoglobin rise of ~1 g/dL per 3 weeks
Rheumatologic effect at 4-8 weeks; ectopic resolution over 2-3 weeks
Rheumatologic effect at 6-12 weeks
SC: 5-15 minutes (Fiasp 2.5 minutes earlier on average)
SC: 5-15 minutes; ultra-rapid Lyumjev faster
SL/spray: 1-3 minutes; IV: minutes; patch: 30-60 minutes
SL: 2-5 minutes; PO mononitrate: 30-60 minutes
Seconds
Sedation from first dose; neuroleptic effect emerges over days to weeks
Sedation/dizziness within hours of oral dose; endometrial effects over days
Serum urate falls gradually over days to weeks; acute flare prevention requires colchicine cover during initiation
Significant antidepressant response by week 1 in trials (faster than monoaminergic antidepressants which take 4-6 weeks)
Sleep effect from first dose; analgesic and migraine-prophylaxis effect 1-4 weeks; antidepressant effect 4-6 weeks
Sleep effect within 30-60 minutes; antidepressant effect over 1-2 weeks
Slow, 2–6 h
Slowing of cognitive decline over 18 months (modest effect, ~27% relative slowing)
Smoked 2-5 min; insufflated 5-15 min; oral 30-60 min; IV / IM ~5-15 min
Sublingual analgesic effect 30-60 minutes; MOUD craving suppression within hours; Butrans patch steady-state in 3 days.
Symptom improvement within 1 week; peak effect at 4-6 weeks
Symptom improvement within 1-2 weeks
Symptom improvement within weeks
Symptom relief 1-4 days; full acid suppression after 3-5 days of dosing
Symptom relief within 24-48 hours
Symptom relief within 24-48 hours of starting episodic treatment
Symptom relief within 30 minutes
Symptom relief within 30-60 minutes
Symptom relief within days
Symptom shortening detectable within 24-48 hours of starting (small absolute benefit; ~1 day reduction in symptom duration)
Symptomatic effect within weeks; full response by 12-24 weeks
Symptomatic improvement 2-4 weeks
TSH normalization 4-8 weeks
TSH normalization 4-8 weeks; symptomatic improvement weeks to months
Topical hours; intra-articular days to weeks
Topical hours; oral days
Topical: inflammation, erythema, crusting at 2 weeks; complete response weeks to months after course
Topical: irritation within days; acne improvement 6-12 weeks; oral APL response within days
Triglyceride lowering at 2-4 weeks; max at 8 weeks
Triglyceride lowering at 4-8 weeks
Triglyceride lowering at 4-8 weeks; CV benefit emerges over months
Typical antidepressant 4-6 week onset
Urinary concentration adequate within hours
Vasomotor relief 2-4 weeks; bone density gains over months
Visible lightening at 4-12 weeks
Wake-promoting effect over weeks of titration
Weeks for psychosis/depression; AD agitation benefit emerges over weeks
Weeks for psychosis/mood efficacy
Weeks to raise 25(OH)D into reference range
Within 30 minutes (IR)
Within hours of first administration
Within minutes
~15 min (fastest of the PDE5 inhibitors)
~15–30 min
~20–40 min PO; faster sublingual/intranasal.
~30 minutes (oral)
~30-60 min
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