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Medicines > generic: Ropinirole & onset : Contraception within 48 hours of starting (POP); endometrial effects days or Motor improvement over days at therapeutic dose

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generic: (Click arrow to add another value)
brand:
Requip (IR), Requip XL (extended-release) (1)
classes:
[[:Category:Antiparkinsonians|Antiparkinsonian]] (1) · [[:Category:Dopamine agonists|Dopamine D2/D3 receptor agonist (non-ergot)]] (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-00000013-QINU`"', '"`UNIQ--vote-00000014-QINU`"' (1)
starting dose:
Parkinson disease: 0.25 mg PO TID, titrate weekly. Restless legs syndrome: 0.25 mg PO 1-3 hours before bedtime, titrate to 4 mg/day if needed (1)
preparations:
IR tablets 0.25, 0.5, 1, 2, 3, 4, 5 mg; XL tablets 2, 4, 6, 8, 12 mg (1)
fda max:
24 mg/day (Parkinson disease); 4 mg/day (restless legs syndrome) (1)
routes:
Oral (1)
onset: (Click arrow to add another value)
duration:
TID dosing (IR); once-daily (XL) (1)
halflife:
~6 hours'"`UNIQ--ref-00000015-QINU`"' (1)
bioavailability:
~55% (oral)'"`UNIQ--ref-00000016-QINU`"' (1)
pregnancy:
Limited human data.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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