Drilldown: Medicines
Use the filters below to narrow your results.
generic:
brand:
classes:
Antidepressant (1) ·
Anxiolytic (1) ·
Dual orexin receptor antagonist (DORA) (1) ·
Serotonin partial agonist reuptake inhibitor (SPARI) (1) ·
SNRI (1) ·
the first approved (1) ·
[[:Category:Anesthetics|Anesthetic]] (1) ·
[[:Category:Antiarrhythmics|Antiarrhythmic (Vaughan Williams Class IB)]] (1) ·
[[:Category:Local anesthetics|Local anesthetic (amide class)]] (1)
mechanism:
uses:
Depression, anxiety, neuropathic pain, fibromyalgia, chronic musculoskeletal pain (1) ·
Insomnia (sleep onset and/or maintenance) in adults (FDA-approved August 2014). Also studied for insomnia in mild-moderate Alzheimer disease. (1) ·
Major depressive disorder in adults (FDA-approved 2011) (1) ·
'"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"' (1)
starting dose:
None (1) ·
10 mg PO 30 min before bedtime (with ≥7 hours of sleep planned) (1) ·
10 mg PO once daily × 7 days, then 20 mg × 7 days, then 40 mg as target dose (take with food) (1) ·
Infiltration: 1-2% solution; '''4.5 mg/kg ceiling without epinephrine, 7 mg/kg with epinephrine'''. IV antiarrhythmic: 1-1.5 mg/kg bolus then infusion 1-4 mg/minute. Lidoderm patch: up to 3 patches per 12 hours (1)
preparations:
fda max:
routes:
onset:
4-6 weeks for full antidepressant effect (claimed earlier onset for some patients due to 5HT1A partial agonism) (1) ·
<1 minute (IV); 1-2 minutes (infiltration); 30+ minutes (patch on adult skin, faster on thinner pediatric skin) (1) ·
Mood: 2–4 weeks. Pain: often within 1–2 weeks. (1) ·
~30 min (1)
duration:
halflife: (Click arrow to add another value)
bioavailability:
pregnancy:
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There are no results for this report.