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Medicines > routes: buccal); refined cocaine has its own profile & halflife : 2–3 h (parent compound) or None

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generic:
Coca (1)
brand:
''Erythroxylum coca'', ''E. novogranatense'' (1)
classes:
Excitantia (1) · Plant Medicine (1)
mechanism:
Primary alkaloid is cocaine, a tropane that blocks reuptake of dopamine and norepinephrine (and serotonin). At low oral doses from leaf chewing, the slow release favors NE-mediated alertness over DA-mediated euphoria. (1)
uses:
'"`UNIQ--vote-0000000C-QINU`"', '"`UNIQ--vote-0000000D-QINU`"', '"`UNIQ--vote-0000000E-QINU`"', '"`UNIQ--vote-0000000F-QINU`"' (1)
starting dose:
None (1)
preparations:
Leaves chewed with a pinch of slaked lime (the lime converts cocaine HCl to freebase for buccal absorption); also drunk as tea (''mate de coca'') (1)
fda max:
None (1)
routes: (Click arrow to add another value)
onset:
None (1)
duration:
None (1)
halflife: (Click arrow to add another value)
bioavailability:
None (1)
pregnancy:
None (1)
legal:
Leaves legal in Bolivia, Peru, Colombia; cocaine internationally controlled (1)

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