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Drilldown: Medicines

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Medicines > routes : IM or Topical ophthalmic & halflife: 3-6 hours (longer in hepatic impairment)'"`UNIQ--ref-00000378-QINU`"'

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generic:
Ondansetron (1)
brand:
Zofran, Zofran ODT (1)
classes:
[[:Category:5-HT3_antagonists|5-HT3 receptor antagonist]] (1) · [[:Category:Antiemetics|Antiemetic]] (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-00000374-QINU`"', '"`UNIQ--vote-00000375-QINU`"', '"`UNIQ--vote-00000376-QINU`"', '"`UNIQ--vote-00000377-QINU`"' (1)
starting dose:
4-8 mg PO or IV every 8 hours as needed; 16 mg single dose preoperatively for PONV prevention (1)
preparations:
4 mg, 8 mg, 24 mg tablets; 4 mg, 8 mg orally disintegrating tablets; 4 mg/5 mL oral solution; IV (2 mg/mL) (1)
fda max:
Single doses ≤16 mg (FDA 2012 advisory withdrew the 32 mg single IV dose for QT-prolongation risk); 24-32 mg/d divided (1)
routes: (Click arrow to add another value)
onset:
30 minutes PO; minutes IV (1)
duration:
4-12 hours (1)
halflife: (Click arrow to add another value)
bioavailability:
~60% (oral)'"`UNIQ--ref-00000379-QINU`"' (1)
pregnancy:
None (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)
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