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Drilldown: Medicines

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Medicines > routes : Topical or None & halflife: Not meaningfully described (topical local action)'"`UNIQ--ref-00001239-QINU`"'

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generic:
Ciclopirox (1)
brand:
Penlac (nail lacquer), Loprox (cream/lotion/shampoo) (1)
classes:
[[:Category:Antifungals|Antifungal]] (1) · [[:Category:Hydroxypyridones|Hydroxypyridone]] (1) · [[:Category:Topical_antifungals|Topical antifungal]] (1)
mechanism:
'"`UNIQ--vote-00001233-QINU`"' Onychomycosis cure rates with nail lacquer are modest (mycologic cure ~30-50%, complete cure ~5-12% at 48 weeks); oral terbinafine remains substantially more effective when systemic therapy is acceptable'"`UNIQ--ref-00001234-QINU`"'. (1)
uses:
'"`UNIQ--vote-00001235-QINU`"', '"`UNIQ--vote-00001236-QINU`"', '"`UNIQ--vote-00001237-QINU`"', '"`UNIQ--vote-00001238-QINU`"' (1)
starting dose:
Topical cream/lotion BID; shampoo twice weekly; nail lacquer (Penlac) once daily for up to 48 weeks (1)
preparations:
0.77% topical cream, lotion, suspension; 1% shampoo; 8% nail lacquer (Penlac) (1)
fda max:
BID topical; once daily nail lacquer (1)
routes: (Click arrow to add another value)
onset:
Days for dermatophyte clearance; nail clearance over months (1)
duration:
Hours per application (1)
halflife: (Click arrow to add another value)
bioavailability:
Topical with minimal systemic absorption'"`UNIQ--ref-0000123A-QINU`"' (1)
pregnancy:
Generally considered safe (minimal systemic absorption).<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)
Error in "where" parameter: the string "--" cannot be used within #cargo_query.

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