Jump to content

Drilldown: Medicines

Nav

Choose a table:

Medicines (732)

Medicines > pregnancy

: Category C

or Category C (not relevant; not used in women)

& legal: Rx-only in US

Use the filters below to narrow your results.

Avanafil (1) · Bisoprolol (1) · Metoprolol (1) · Nebivolol (1) · Prazosin (1) · Propranolol (1)

Bystolic (1) · Inderal (1) · Lopressor (tartrate), Toprol XL (succinate) (1) · Minipress (1) · Stendra (1) · Zebeta (1)

Alpha-1 Adrenergic Antagonist (1) · Beta Blocker (4) · Cardioselective (β1) (2) · Cardioselective (β1) + vasodilator (1) · Non-selective (1) · PDE5 Inhibitor (1)

Cardioselective β1-adrenergic antagonist. Selectivity is dose-dependent and partially lost at higher doses. (1) · Highly β1-selective adrenergic antagonist. Greater selectivity than metoprolol or atenolol. (1) · Non-selective competitive antagonist at β1 and β2 adrenergic receptors. Lipophilic; significant blood–brain barrier penetration, accounting for its CNS effects. (1) · Selective alpha-1 adrenergic receptor antagonist. Lowers peripheral vascular resistance via vasodilation; in the CNS, blunts noradrenergic hyperarousal thought to drive trauma-related nightmares. (1) · Selective inhibitor of phosphodiesterase type 5 (PDE5); increases cGMP in cavernous smooth muscle, producing erection in response to sexual stimulation. (1) · The d-enantiomer is a highly β1-selective antagonist; the l-enantiomer triggers endothelial nitric-oxide–mediated vasodilation. Unique among beta blockers for this NO mechanism. (1)

'"`UNIQ--vote-00000040-QINU`"' (1) · '"`UNIQ--vote-000004F5-QINU`"', '"`UNIQ--vote-000004F6-QINU`"', '"`UNIQ--vote-000004F7-QINU`"', '"`UNIQ--vote-000004F8-QINU`"', '"`UNIQ--vote-000004F9-QINU`"' (1) · '"`UNIQ--vote-0000059D-QINU`"' (1) · '"`UNIQ--vote-000005D0-QINU`"', '"`UNIQ--vote-000005D1-QINU`"', '"`UNIQ--vote-000005D2-QINU`"' (1) · '"`UNIQ--vote-000005E7-QINU`"', '"`UNIQ--vote-000005E8-QINU`"', '"`UNIQ--vote-000005E9-QINU`"', '"`UNIQ--vote-000005EA-QINU`"', '"`UNIQ--vote-000005EB-QINU`"' (1) · '"`UNIQ--vote-00000636-QINU`"', '"`UNIQ--vote-00000637-QINU`"', '"`UNIQ--vote-00000638-QINU`"' (1)

1 mg at bedtime (PTSD nightmares); 1 mg BID–TID (HTN) (1) · 100 mg ~15 min before sexual activity (1) · 10–40 mg (situational anxiety); 40 mg BID (HTN) (1) · 2.5–5 mg daily (HTN); 1.25 mg daily (HFrEF, slow titration) (1) · 25–50 mg BID (tartrate); 25–100 mg daily (succinate); 12.5 mg daily in HFrEF (1) · 5 mg daily (1)

1, 2, 5 mg caps (1) · 10, 20, 40, 60, 80 mg tabs; 60/80/120/160 mg ER caps; 1 mg/mL IV (1) · 2.5, 5, 10, 20 mg tabs (1) · 5, 10 mg tabs (1) · 50, 100, 200 mg tabs (1) · Tartrate: 25, 50, 100 mg tabs; 1 mg/mL IV. Succinate ER: 25, 50, 100, 200 mg. (1)

20 mg/d (1) · 200 mg/d (100 mg/d if on CYP3A4 inhibitors) (1) · 40 mg/d (2) · 400 mg/d (1) · 640 mg/d (HTN); 240 mg/d (migraine) (1)

IV (2) · Oral (6)

1–2 h (2) · 1–2 h (PO), immediate (IV) (1) · 1–2 h (PO); immediate (IV) (1) · 30–90 min (1) · ~15 min (fastest of the PDE5 inhibitors) (1)

24 h (2) · 4–6 h (1) · 6–12 h (IR); 24 h (ER) (1) · 6–12 h (tartrate); 24 h (succinate) (1) · 6–8 h (1)

2–3 h (1) · 3–6 h (1) · 3–7 h (1) · 9–12 h (1) · ~10 h (CYP2D6 extensive metabolizers); up to 31 h (poor metabolizers) (1) · ~5 h (1)

Rapid absorption; absolute bioavailability not formally established (1) · ~12% (extensive metabolizers); ~96% (poor metabolizers) (1) · ~25% (extensive hepatic first-pass) (1) · ~50% (1) · ~60% (1) · ~90% (low first-pass) (1)

Showing below up to 6 results in range #1 to #6.

A

Avanafil

B

Bisoprolol

M

Metoprolol

N

Nebivolol

P

Retrieved from "https://pharmacopedia.wiki/p/Special:Drilldown/Medicines"