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Drilldown: Medicines

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Medicines > mechanism: None & legal: [[USLegal:Prescription only|Rx-only]] in US

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generic:
brand:
classes:
[[:Category:Antihypertensives|Antihypertensive]] (10) · [[:Category:Lipid-lowering_agents|Lipid-lowering agent]] (6) · [[:Category:Analgesics|Analgesic]] (5) · [[:Category:Beta-lactam_antibiotics|β-lactam antibiotic]] (5) · [[:Category:Antianginals|Antianginal]] (4) · [[:Category:Antihyperglycemic_agents|Antihyperglycemic agent]] (4) · [[:Category:BPH_treatments|Benign prostatic hyperplasia treatment]] (4) · [[:Category:Glaucoma_medications|Glaucoma medication]] (4) · [[:Category:Ocular_hypotensive_agents|Ocular hypotensive agent]] (4) · [[:Category:Antimigraine medicines|Antimigraine medicine]] (3) · [[:Category:Antimuscarinics|Antimuscarinic]] (3) · [[:Category:Antineoplastics|Antineoplastic]] (3) · [[:Category:Corticosteroids|Corticosteroid]] (3) · [[:Category:Immunosuppressants|Immunosuppressant]] (3) · [[:Category:Statins|Statin]] (3)
mechanism: (Click arrow to add another value)
uses:
'"`UNIQ--vote-00000017-QINU`"', '"`UNIQ--vote-00000018-QINU`"', '"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"' (4) · '"`UNIQ--vote-00000013-QINU`"', '"`UNIQ--vote-00000014-QINU`"' (3) · '"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"' (2)
starting dose:
preparations:
fda max:
10 mg/d (2) · 4 g/d (2) · 40 mg/d (2) · 5 mg/d (2) · Indication-specific (2) · TID per eye (2)
routes:
Oral (63) · IV (22) · IM (8) · topical (7) · subcutaneous (5) · Topical ophthalmic (4) · intranasal (3) · ophthalmic (3) · rectal (3) · transdermal (3) · vaginal (3) · intramuscular (2) · intravitreal (2)
onset:
Hours (8) · 1-2 hours (2) · Clinical improvement within 24-72 hours (2) · LDL lowering at 2 weeks, max by 4 weeks (2) · Motor improvement over days at therapeutic dose (2)
duration:
24 hours (17) · 12 hours (3) · 12-24 hours (3) · 4-6 hours (3) · 8-12 hours (3) · 6-8 hours (2) · N/A (2)
halflife:
bioavailability:
~100% (oral)'"`UNIQ--ref-0000001C-QINU`"' (2)
pregnancy:
None (6) · Limited data.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (5) · Avoid in second and third trimesters; fetal SGLT2 inhibition disrupts kidney development.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (2) · Generally considered safe in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (2) · Generally considered safe; widely used.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (2) · Limited data; weigh against alternatives.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (2) · Limited human data.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (2) · Limited human data; rarely indicated in pregnancy given the patient population.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (2) · Previously Category X; FDA removed the blanket statin contraindication in pregnancy in 2021.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (2)
legal: (Click arrow to add another value)

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