Drilldown: Medicines
Medicines > routes:
Oral 
& onset :
Day 3 of dosing in trials; sustained through day 45 or
Postprandial glucose effect within days; HbA1c by 12 weeks
& onset :
Day 3 of dosing in trials; sustained through day 45 or
Postprandial glucose effect within days; HbA1c by 12 weeks Use the filters below to narrow your results.
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None (1) ·
Synthetic neuroactive steroid (an analog of allopregnanolone), bioavailable orally unlike brexanolone. Positive allosteric modulator at GABA-A receptors including extrasynaptic δ-containing subtypes. (1) ·
'"`UNIQ--vote-00000762-QINU`"' Largely renally cleared, hence the eGFR-tiered dosing. Rare but well-documented signals: acute pancreatitis (uncertain causal contribution), severe joint pain, and bullous pemphigoid (class effect, especially in older Asian patients)'"`UNIQ--ref-00000763-QINU`"'. (1)
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Showing below up to 3 results in range #1 to #3.