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Medicines > routes: Topical ophthalmic & onset : IOP lowering at 3-4 hours; maximum at 8-12 hours or None

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generic:
Latanoprost (1)
brand:
Xalatan, Xelpros (1)
classes:
[[:Category:Glaucoma_medications|Glaucoma medication]] (1) · [[:Category:Ocular_hypotensive_agents|Ocular hypotensive agent]] (1) · [[:Category:Prostaglandin_analogs|Prostaglandin F2α analog]] (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-00000415-QINU`"', '"`UNIQ--vote-00000416-QINU`"' (1)
starting dose:
1 drop in the affected eye(s) once daily in the evening (1)
preparations:
0.005% ophthalmic solution (50 mcg/mL); typical 2.5 mL bottle (1)
fda max:
1 drop/eye/day (more frequent dosing reduces efficacy) (1)
routes: (Click arrow to add another value)
onset: (Click arrow to add another value)
duration:
24 hours (1)
halflife:
~17 minutes (free acid, the active form, in aqueous humor)'"`UNIQ--ref-00000417-QINU`"' (1)
bioavailability:
Topical; minimal systemic absorption'"`UNIQ--ref-00000418-QINU`"' (1)
pregnancy:
Limited data; weigh against alternatives, though systemic exposure is low.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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