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Medicines > routes : Subcutaneous (abdomen or oral powder (Cambia for migraine) & onset: Glycemic effect within days; weight effect over weeks to months'"`UNIQ--ref-00000188-QINU`"'

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generic:
Liraglutide (1)
brand:
Victoza (T2DM), Saxenda (obesity) (1)
classes:
[[GLP-1 receptor agonist]] · [[Antidiabetic medicines|Antidiabetic]] · [[Anti-obesity medicines|Anti-obesity]] · [[Cardiovascular risk reduction]] agent (1)
mechanism:
Once-daily agonist of the [[GLP-1 receptor]]. (1)
uses:
[[Type 2 diabetes mellitus]] (incl. pediatric ≥10 y) · [[Obesity]] (incl. pediatric ≥12 y) · [[Cardiovascular risk reduction]] in T2DM (1)
starting dose:
Victoza: 0.6 mg SC daily × 1 wk'"`UNIQ--ref-00000181-QINU`"' · Saxenda: 0.6 mg SC daily × 1 wk'"`UNIQ--ref-00000182-QINU`"' (1)
preparations:
Pre-filled multi-dose pen (3 mL): Victoza 6 mg/mL (0.6 / 1.2 / 1.8 mg per day);'"`UNIQ--ref-00000183-QINU`"' Saxenda 6 mg/mL (0.6 / 1.2 / 1.8 / 2.4 / 3.0 mg per day)'"`UNIQ--ref-00000184-QINU`"' (1)
fda max:
1.8 mg/day SC (Victoza, T2DM)'"`UNIQ--ref-00000185-QINU`"' · 3.0 mg/day SC (Saxenda, obesity)'"`UNIQ--ref-00000186-QINU`"' (1)
routes: (Click arrow to add another value)
onset: (Click arrow to add another value)
duration:
~24 h (daily dosing)'"`UNIQ--ref-00000189-QINU`"' (1)
halflife:
~13 hours'"`UNIQ--ref-0000018A-QINU`"' (1)
bioavailability:
SC ~55%'"`UNIQ--ref-0000018B-QINU`"' (1)
pregnancy:
Avoid. Discontinue before planned pregnancy.'"`UNIQ--ref-0000018C-QINU`"' (1)
legal:
Rx-only;'"`UNIQ--ref-0000018D-QINU`"' not a controlled substance (1)
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